spo0M
168
sporulation-control gene
locus
BSU_08760
Molecular weight
29.56 kDa
pI
4.28
function
sporulation
product
unknown
essential
no
synonyms
spo0M, ygaI
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4326 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
953,373 954,149
Phenotypes of a mutant
Blocked at stage zero of [wiki|sporulation] and is susceptible to lysis during vegetative growth [Pubmed|9795118]
The protein
Protein family
spo0M family (single member, according to UniProt)
Structure
[PDB|5CL2] [Pubmed|26625291]
[AF|P71088]
Effectors of protein activity
the protein is degraded by the [protein|4E7B9426CED372AA8A321A147116A3A589FBF20C|ftsH] metalloprotease [Pubmed|22142536]
[wiki|Localization]
scattered distribution pattern in cells, appearing near the cell poles and the septum region [pubmed|28234965]
Expression and Regulation
Operons
genes
[gene|86BEE9B4DEA83B3B8EFC52EFDDC1F62314FC4291|spo0M]
description
[Pubmed|9795118]
sigma factors
[protein|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|sigH]: sigma factor, [Pubmed|9795118], in [regulon|protein:DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|sigH regulon]
[protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|sigW]: sigma factor, [Pubmed|11866510], in [regulon|protein:3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|sigW regulon]
additional information
the protein is degraded by the [protein|search|FtsH] metalloprotease [PubMed|22142536]
Biological materials
Mutant
BKE08760 ([gene|86BEE9B4DEA83B3B8EFC52EFDDC1F62314FC4291|spo0M]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE08760 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTAGATCTTCCCCTTT, downstream forward: _UP4_TAAGTATAAAAAGGAGCCGA
BKK08760 ([gene|86BEE9B4DEA83B3B8EFC52EFDDC1F62314FC4291|spo0M]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK08760 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTAGATCTTCCCCTTT, downstream forward: _UP4_TAAGTATAAAAAGGAGCCGA
References
Reviews
Original Publications
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Time of last update: 2024-12-26 19:17:32
Author of last update: Melvin.boenninger