licH
168
6-phospho-beta-glucosidase
locus
BSU_38560
Molecular weight
48.55 kDa
pI
5.18
function
lichenan utilization
product
6-phospho-beta-glucosidase
essential
no
ec
3.2.1.86
synonyms
licH, celD, celF
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1486 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,958,516 3,959,844
The protein
Catalyzed reaction/ biological activity
6-phospho-β-D-glucosyl-(1→4)-D-glucose + H2O --> D-glucose + D-glucose 6-phosphate (according to UniProt)
Protein family
[wiki|Glycosyl hydrolase 4 family] (according to UniProt)
Structure
[PDB|1S6Y] (Geobacillus stearothermophilus)
[AF|P46320]
Expression and Regulation
Operons
genes
[gene|65FC7F4ED92F747DB7BC5672DCA2D2320A471134|licB]-[gene|83A7C160B0301A2B51B65478D99ACB753D67AF74|licC]-[gene|E8B6C8E722BEE866878CDD816B7828C132F94FCD|licA]-[gene|84D8AA0AFBF46273F6B4198B49440D55470FEC0F|licH]
description
[Pubmed|8990303]
regulation
carbon catabolite repression ([protein|search|CcpA]) [Pubmed|8990303]
regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|8990303], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
[protein|E087ABA705CE94E2CAD44A0F2FB265B0F7B04399|licR]: activation, [Pubmed|8990303], in [regulon|protein:E087ABA705CE94E2CAD44A0F2FB265B0F7B04399|licR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|8990303], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
BKE38560 ([gene|84D8AA0AFBF46273F6B4198B49440D55470FEC0F|licH]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE38560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CGTTACAATCTTCAATCCTT, downstream forward: _UP4_TAAAAAAAGCCGGCCTGTAA
BKK38560 ([gene|84D8AA0AFBF46273F6B4198B49440D55470FEC0F|licH]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK38560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CGTTACAATCTTCAATCCTT, downstream forward: _UP4_TAAAAAAAGCCGGCCTGTAA
References
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Time of last update: 2024-12-21 17:30:02
Author of last update: Melvin.boenninger