lctP
168
lactate permease, excretion
locus
BSU_03060
Molecular weight
57.49 kDa
pI
9.77
function
lactate excretion
product
L-lactate permease
essential
no
synonyms
lctP, ycgC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1620 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
330,771 332,396
The protein
Protein family
lactate permease family (with [protein|E607B0D57398BCCF64CF3CE2110E632B0C3A109E|lutP], according to UniProt)
Structure
[AF|P55910]
Paralogous protein(s)
[protein|E607B0D57398BCCF64CF3CE2110E632B0C3A109E|lutP]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|A0DD68FE90FD13DF03496321AB2DAAADF9F4230D|ldh]-[gene|84D391ED4E81BC17FC2A115985962445D7996DFA|lctP]
description
[Pubmed|16207915]
regulation
induced under anaerobic conditions ([protein|search|Rex]) [Pubmed|16207915]
regulatory mechanism
[protein|B5EF521437323EF43F08E5EFDB5C798616CA499A|rex]: repression, [Pubmed|16207915], in [regulon|protein:B5EF521437323EF43F08E5EFDB5C798616CA499A|rex regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|10809684], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
BKE03060 ([gene|84D391ED4E81BC17FC2A115985962445D7996DFA|lctP]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03060 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGACAATCAGCCCTTTA, downstream forward: _UP4_TAATAGAAAAAAGCAGTACA
BKK03060 ([gene|84D391ED4E81BC17FC2A115985962445D7996DFA|lctP]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03060 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGACAATCAGCCCTTTA, downstream forward: _UP4_TAATAGAAAAAAGCAGTACA
GP2578 ([gene|84D391ED4E81BC17FC2A115985962445D7996DFA|lctP]::tet comIQ12L) (in DK1042) available in [wiki|Jörg Stülke]'s lab
References
Page visits: 4366
Time of last update: 2024-10-10 09:27:13
Author of last update: Melvin.boenninger