opuCB
168
glycine betaine/carnitine/choline/arsenobetaine/arsenocholine [wiki|ABC transporter]
locus
BSU_33820
Molecular weight
23.00 kDa
pI
9.7
function
compatible solute transport
product
glycine betaine/carnitine/choline/arsenobetaine/arsenocholine [wiki|ABC transporter]
essential
no
synonyms
opuCB, yvbD
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1174 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,469,184 3,469,837
The protein
Catalyzed reaction/ biological activity
uptake of glycine betaine, arsenocholine and arsenobetaine [pubmed|29159878]
Protein family
[wiki|Binding-protein-dependent transport system permease family] (according to UniProt)
[wiki|CysTW subfamily] (according to UniProt)
[wiki|Domains]
[wiki|ABC transmembrane type-1 domain] (aa 19-198) (according to UniProt)
Structure
[AF|O34878]
Paralogous protein(s)
[protein|70B45E7428DB1F6AEF7D2FE3062CC86BE96674FC|opuBB]
[wiki|Localization]
cell membrane [Pubmed|10092453]
Expression and Regulation
Operons
genes
[gene|75DB6231129C28C5D3791BA43A1261CD46A861E8|opuCA]-[gene|83C45215AC86FACB08CF36EB5F9E6B076D7D0F0F|opuCB]-[gene|CBA6108A10AD8B932BC5B19A0E7982D0F56F1E08|opuCC]-[gene|76C8D6BF2CA1FA5E7392C52FFD55FD01EF5AB9DC|opuCD]
description
[Pubmed|10216873]
regulation
induced by salt stress [Pubmed|23960087,10216873]
induced in the absence of [protein|F4097349A563503468A2A14F062AEAC532C7917A|rnpM] [pubmed|30355672]
regulatory mechanism
[protein|9F32E96AC9C32832C2F10FB125DDDC50EC9B546B|opcR]: repression, (sterical interference with RNA polymerase access) [Pubmed|32849357,23960087], in [regulon|protein:9F32E96AC9C32832C2F10FB125DDDC50EC9B546B|opcR regulon]
[protein|6AF1CB8998BE9C71DF4F1201A7F74FF7E75CB799|remA]: activation, [Pubmed|23646920], in [regulon|protein:6AF1CB8998BE9C71DF4F1201A7F74FF7E75CB799|remA regulon]
[protein|F4097349A563503468A2A14F062AEAC532C7917A|rnpM]: unknown, [pubmed|30355672], in [regulon|protein:F4097349A563503468A2A14F062AEAC532C7917A|rnpM regulon]
Biological materials
Mutant
BKE33820 ([gene|83C45215AC86FACB08CF36EB5F9E6B076D7D0F0F|opuCB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTTAAAAGAGCTCCTCC, downstream forward: _UP4_TCGTAAGGAGTTGGCACTGT
BKK33820 ([gene|83C45215AC86FACB08CF36EB5F9E6B076D7D0F0F|opuCB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTTAAAAGAGCTCCTCC, downstream forward: _UP4_TCGTAAGGAGTTGGCACTGT
References
Reviews
Original Publications
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Time of last update: 2024-12-21 19:54:12
Author of last update: Jstuelk