rpeA
168
ribulose 5-phosphate 3-epimerase
locus
BSU_15790
Molecular weight
23.19 kDa
pI
5.65
function
pentose phosphate pathway
product
ribulose 5-phosphate 3-epimerase
essential
no
ec
5.1.3.1
synonyms
rpe, yloR
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0036 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,654,004 1,654,657
Phenotypes of a mutant
the mutant cells are shorter than wild type cells [pubmed|34846166]
The protein
Catalyzed reaction/ biological activity
D-ribulose 5-phosphate --> D-xylulose 5-phosphate (according to UniProt)
Protein family
ribulose-phosphate 3-epimerase family (single member, according to UniProt)
Structure
[PDB|1TQJ] (from ''Synechocystis sp.'', 61% identity, 75% similarity) [Pubmed|15333955]
[AF|O34557]
Expression and Regulation
Operons
genes
[gene|84447F9A6644EA8A7593BB99B2B69D4377E670E2|prpC]-[gene|23FF4A00C36EC1B7297F51A9EF3579B41F0B7EBA|prkC]-[gene|519D4694B2895EE6F0D38D918F52F27734506848|cpgA]-[gene|8103B8539338B77CF51B16B7FA76783ED2319F13|rpeA]-[gene|0ACE023DCD6A6BB5A1827D1D997BDFAC3B168C51|yloS]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-B374 (yloR::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1373 NBRP B. subtilis, Japan]
BKE15790 ([gene|8103B8539338B77CF51B16B7FA76783ED2319F13|rpeA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE15790 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AGATGGTGCAACCTTTATCA, downstream forward: _UP4_TAAGCAGCTTTAGAAAAGAG
BKK15790 ([gene|8103B8539338B77CF51B16B7FA76783ED2319F13|rpeA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK15790 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AGATGGTGCAACCTTTATCA, downstream forward: _UP4_TAAGCAGCTTTAGAAAAGAG
FLAG-tag construct
GP1405 (spc, based on [wiki|pGP1331]), available in [wiki|Jörg Stülke]'s lab
References
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Time of last update: 2025-04-03 15:07:20
Author of last update: Jstuelk