sigY
168
[wiki|RNA polymerase] ECF-type [wiki|sigma factor] SigY
locus
BSU_38700
Molecular weight
21.21 kDa
pI
9.55
function
maintenance of the SP prophage
product
[wiki|RNA polymerase] ECF-type [wiki|sigma factor] SigY
essential
no
synonyms
sigY, yxlB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1595 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,970,312 3,970,848
Phenotypes of a mutant
loss of the [[SP prophage]] [Pubmed|22400495]
sensitive to killing by [protein|1A6D90298D039FFFD977B2534952BA5E32B3530F|sublancin]]] [Pubmed|22400495]
no production of [protein|1A6D90298D039FFFD977B2534952BA5E32B3530F|sublancin]]] [Pubmed|22400495]
The protein
Protein family
[wiki|Sigma-70 factor family] (according to UniProt)
[wiki|ECF subfamily] (according to UniProt)
Structure
[PDB|5WUQ] (the [protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|sigW]-[protein|4E720917045032E8B45CB8AF6E5C13AE0E48EE33|rsiW] complex, 30% identity) [pubmed|28319136]
[AF|P94370]
Expression and Regulation
Operons
genes
[gene|801E92306971E26AD4AB155172B7F4EFDE2F9170|sigY]-[gene|C07156CBA0AA3BAB24D17D15708FC68E74A854A7|yxlC]-[gene|CAADFAFD4C39362D0D0F242C926AE101C683EB5D|yxlD]-[gene|B40D01DDD9EF8B64E46CA7DBF4BAC3DBF8A73986|yxlE]-[gene|D246F61BEAE0D3D6707B4C43A634C02876CC5395|yxlF]-[gene|DCC03844AC58A198B851B564D0A6459C39EBDA2F|yxlG]
description
[Pubmed|14769884]
sigma factors
[protein|801E92306971E26AD4AB155172B7F4EFDE2F9170|sigY]: sigma factor, [Pubmed|12897008], in [regulon|protein:801E92306971E26AD4AB155172B7F4EFDE2F9170|sigY regulon]
Biological materials
Mutant
MGNA-B751 (sigY::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1750 NBRP B. subtilis, Japan]
1A909 ( ''sigY''::''erm''), [Pubmed|12897008], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A909&Search=1A909 BGSC]
BKE38700 ([gene|801E92306971E26AD4AB155172B7F4EFDE2F9170|sigY]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE38700 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGACCGTGATCCCCCCT, downstream forward: _UP4_CAGCAAATCAGAAAGGAGTG
BKK38700 ([gene|801E92306971E26AD4AB155172B7F4EFDE2F9170|sigY]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK38700 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGACCGTGATCCCCCCT, downstream forward: _UP4_CAGCAAATCAGAAAGGAGTG
References
Reviews
Other original publications
The [wiki|SigY regulon]
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Time of last update: 2024-10-10 07:20:57
Author of last update: Jstuelk