cdsA
168
phosphatidate cytidylyltransferase
locus
BSU_16540
Molecular weight
30.06 kDa
pI
7.87
function
biosynthesis of phospholipids
product
phosphatidate cytidylyltransferase
essential
yes
ec
2.7.7.41
synonyms
cdsA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0575 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,722,000 1,722,809
Phenotypes of a mutant
essential [Pubmed|12682299]
The protein
Catalyzed reaction/ biological activity
1,2-diacyl-sn-glycero-3-phosphate + CTP + H+ --> CDP-1,2-diacyl-sn-glycerol + diphosphate (according to UniProt)
Protein family
CDS family (single member, according to UniProt)
Structure
[PDB|4Q2G] (from ''Thermotoga maritima'', 36% identity) [Pubmed|24968740]
[AF|O31752]
[wiki|Localization]
cell membrane at the septum [Pubmed|15743965,19820159]
Expression and Regulation
Operons
genes
[gene|4A637EB9B400D30E5C6246D1E0EB5E6A30F38A16|uppS]-[gene|7E7F6BBA03C443A5AFA05A6D9352FEF1212A5AF6|cdsA]-[gene|58CDF08A8F05C0BC25EB6E400316F85FD0F307E5|ispC]-[gene|CB50289535EA537F63BADD459BD11AA7759A6658|rasP]-[gene|848570563D3C92A8E1E6AB4DA530388D8AE94E75|proS]-[gene|FB97DF0C147FB29944F60214CB9BC1803861DAA0|polC]
description
[Pubmed|22383849]
additional information
the mRNA is very stable (> 15 min) [pubmed|12884008]
References
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Time of last update: 2024-12-19 18:30:43
Author of last update: Melvin.boenninger