mtrA
168
methylthioribose transporter
locus
BSU_07340
Molecular weight
48.74 kDa
pI
9.82
function
uptake of methylthioribose
product
methylthioribose transporter
essential
no
synonyms
mtrA, yfnA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0531 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
805,456 806,841
The protein
Catalyzed reaction/ biological activity
uptake of methylthioribose [pubmed|29280348]
Protein family
[wiki|amino acid-polyamine-organocation (APC) superfamily] (according to UniProt)
Structure
[PDB|5OQT] (from Geobacillus kaustophilus, 60% identity) [pubmed|29416041]
[AF|Q797A7]
Paralogous protein(s)
[protein|210C83EBEBD3DE4946BC511E0249D0032A7CE3D0|bcaP]
[wiki|Localization]
cell membrane [Pubmed|18763711]
Expression and Regulation
Operons
genes
[gene|7E180420EB053D9EF7993EF600A169C446F905F9|mtrA]-[gene|2E1E22349750C3EE9B6575EED30A82ED0D5F07F0|yfnB]
description
[Pubmed|22383849]
genes
[gene|7E180420EB053D9EF7993EF600A169C446F905F9|mtrA]
description
[pubmed|22383849]
Biological materials
Mutant
GP2379 ∆''[gene|7E180420EB053D9EF7993EF600A169C446F905F9|mtrA]''::''kan'', available in [wiki|Jörg Stülke]'s lab [pubmed|32743959]
MGNA-C231 (yfnA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2229 NBRP B. subtilis, Japan]
BKE07340 ([gene|7E180420EB053D9EF7993EF600A169C446F905F9|mtrA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE07340 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAAAAGTTCCTCCTAGA, downstream forward: _UP4_TAATCTCTTTTCAGCCGGCG
BKK07340 ([gene|7E180420EB053D9EF7993EF600A169C446F905F9|mtrA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK07340 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAAAAGTTCCTCCTAGA, downstream forward: _UP4_TAATCTCTTTTCAGCCGGCG
lacZ fusion
pGP2278 (in [wiki|pAC5]) (GP2964), available in [wiki|Jörg Stülke]'s lab
References
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Time of last update: 2024-10-07 07:22:09
Author of last update: Jstuelk