kipR
168
transcriptional repressor of the kip operon
locus
BSU_04100
Molecular weight
27.16 kDa
pI
5.43
function
regulation of [wiki|sporulation] initiation
product
transcriptional regulator
essential
no
synonyms
kipR, ycsO
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1414 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
461,615 462,367
The protein
[wiki|Domains]
HTH iclR-type domain (aa 5-65) (according to UniProt)
IclR-ED (aa 80-249) (according to UniProt)
Structure
[PDB|1MKM] (from Thermotoga maritima, 33% identity) [pubmed|11877432]
[AF|P42968]
Expression and Regulation
Operons
genes
[gene|77F758CE9A59AC41F283CB1F5099097386133799|pxpA]-[gene|9AD419E3CB86C54A0F11E96C82E80A357C6B23D2|ycsG]-[gene|312E2A4ADFBCB9DD9AD9EEEC9FE53F3932AF5DBA|ycsI]-[gene|5A5E17D39296FECC1C03B1A7791AB1065BB4E4DF|pxpB]-[gene|3BA8F1F71B1D65EB30867ABD27867F925DAD2D7B|pxpC]-[gene|7DA9A79876C546B78B716A64706A3A3716018C2E|kipR]-[gene|05910B4500420D4DB75DAD3A7A2358C360FF2154|lipC]
description
[Pubmed|9334321]
regulation
induced in the presence of 5-oxoproline [pubmed|28830929]
regulatory mechanism
[protein|7DA9A79876C546B78B716A64706A3A3716018C2E|kipR]: repression, [Pubmed|9334321], in [regulon|protein:7DA9A79876C546B78B716A64706A3A3716018C2E|kipR regulon]
[protein|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|tnrA]: activation, [Pubmed|9334321], in [regulon|protein:857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|tnrA regulon]
Biological materials
Mutant
BKE04100 ([gene|7DA9A79876C546B78B716A64706A3A3716018C2E|kipR]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE04100 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATTCTGCATCATTCATCCCC, downstream forward: _UP4_TAAGTAGCCAATCTTTTCTC
BKK04100 ([gene|7DA9A79876C546B78B716A64706A3A3716018C2E|kipR]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK04100 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATTCTGCATCATTCATCCCC, downstream forward: _UP4_TAAGTAGCCAATCTTTTCTC
References
Page visits: 3454
Time of last update: 2025-01-04 08:42:56
Author of last update: Melvin.boenninger