mnaA
168
UDP-N-acetylglucosamine 2-epimerase
locus
BSU_35660
Molecular weight
42.48 kDa
pI
5.47
function
biosynthesis of teichoic acid
product
UDP-N-acetylglucosamine 2-epimerase
essential
yes
ec
5.1.3.14
synonyms
mnaA, yvyH
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0381 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,664,241 3,665,383
Phenotypes of a mutant
essential [Pubmed|12682299]
The protein
Catalyzed reaction/ biological activity
UDP-N-acetyl-α-D-glucosamine --> UDP-N-acetyl-α-D-mannosamine (according to UniProt)
Protein family
UDP-N-acetylglucosamine 2-epimerase family (single member, according to UniProt)
Structure
[PDB|1O6C] [Pubmed|16021622]
[AF|P39131]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|7BEAEDC0BE19F490B597BB0A6AEAE006FFBDC1D1|mnaA]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-B651 (yvyH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1650 NBRP B. subtilis, Japan]
References
Reviews
Original Publications
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Time of last update: 2024-12-20 21:48:58
Author of last update: Melvin.boenninger