fbp
168
fructose-1,6-bisphosphatase, involved in gluconeogenesis
locus
BSU_40190
Molecular weight
77.80 kDa
pI
5.6
function
gluconeogenesis
product
fructose-1,6-bisphosphatase
essential
no
ec
3.1.3.11
synonyms
fbp, fdp, yydE
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG3855 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
4,128,029 4,130,044
The protein
Catalyzed reaction/ biological activity
β-D-fructose 1,6-bisphosphate + H2O --> β-D-fructose 6-phosphate + phosphate (according to UniProt)
Protein family
FBPase class 3 family (single member, according to UniProt)
Structure
[AF|Q45597]
Expression and Regulation
Operons
genes
[gene|79DD9B2E2EBB4646327AFC2148CE040823DE89D3|fbp]
description
[pubmed|22383849,9696785]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [pubmed|9696785], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
MGNA-B811 (yydE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1810 NBRP B. subtilis, Japan]
BKE40190 ([gene|79DD9B2E2EBB4646327AFC2148CE040823DE89D3|fbp]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE40190 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAACCGTCCATCCCCTTT, downstream forward: _UP4_TGAGGGGTGTGGGGTTCAGG
BKK40190 ([gene|79DD9B2E2EBB4646327AFC2148CE040823DE89D3|fbp]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK40190 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAACCGTCCATCCCCTTT, downstream forward: _UP4_TGAGGGGTGTGGGGTTCAGG
References
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Time of last update: 2024-12-19 15:42:53
Author of last update: Jstuelk