araE
168
L-arabinose permease (proton symporter)
locus
BSU_33960
Molecular weight
50.25 kDa
pI
9.26
function
uptake of arabinose, galactose and xylose
product
L-arabinose permease
essential
no
synonyms
araE, yvbR
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2814 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,484,072 3,485,466
The protein
Catalyzed reaction/ biological activity
transports arabinose, and also xylose and galactose [Pubmed|9620981]
Protein family
[wiki|major facilitator superfamily] (according to UniProt)
[wiki|Sugar transporter (TC 2.A.1.1) family] (according to UniProt)
Structure
[PDB|4JA4] (the xylose transporter XylE from ''E. coli'', 39% identity, 68% similarity) [Pubmed|23624861]
[AF|P96710]
Paralogous protein(s)
[protein|7CE5A42042E5D52768735E795DB805530691D8A6|ywtG], [protein|8B0701B5694ABA8142476CB896E590FE1981D7DB|yfiG], [protein|A84AC4E40E7C722E27AE9C24ACECFEABD51B57BE|yncC], [protein|0757FAEB38AA1C599C5067794AF83A4BA5912DC9|csbC], [protein|4A77316AA94F9C11DB70AB76711AACBD28098AA1|iolT]
[wiki|Localization]
cell membrane (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|770D9A5BEEEABE9C3FC772E74001329206ECFAB3|araE]
description
[Pubmed|9401028]
regulation
induced by arabinose ([protein|search|AraR]) [Pubmed|9401028,9620981,10417639]
regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|12949161], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
[protein|A567466894AE9DE7CDE7816615433A37532297B5|araR]: repression, [Pubmed|9401028,9620981,10417639], in [regulon|protein:A567466894AE9DE7CDE7816615433A37532297B5|araR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|9401028], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
BKE33960 ([gene|770D9A5BEEEABE9C3FC772E74001329206ECFAB3|araE]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33960 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCCCTGCCCTCCCGAA, downstream forward: _UP4_TGAAAACGCTTTAATGAAAC
BKK33960 ([gene|770D9A5BEEEABE9C3FC772E74001329206ECFAB3|araE]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33960 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCCCTGCCCTCCCGAA, downstream forward: _UP4_TGAAAACGCTTTAATGAAAC
References
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Time of last update: 2024-10-04 15:02:49
Author of last update: Melvin.boenninger