hemY
168
coproporphyrinogen oxidase
locus
BSU_10140
Molecular weight
51.04 kDa
pI
8.04
function
biosynthesis of heme
product
coproporphyrinogen oxidase
essential
no
ec
1.3.3.4
synonyms
hemY, hemG, cgoX
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1232 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,088,197 1,089,609
The protein
Catalyzed reaction/ biological activity
coproporphyrinogen --> coproporphyrin [pubmed|25646457]
3 O2 + protoporphyrinogen IX --> 3 H2O2 + protoporphyrin IX (according to UniProt)
Protein family
Protoporphyrinogen oxidase family (single member, according to UniProt)
[wiki|Cofactors]
FAD [pubmed|37102418]
Structure
[PDB|3I6D]
[AF|P32397]
[wiki|Localization]
cell membrane (peripheral) [pubmed|7928957]
Expression and Regulation
Operons
genes
[gene|762E7731EFEAC9F38074D7A7E9A3E5759437CDCA|hemE]-[gene|E4C588EC93132CCBE4F40559F8A480A66A2D82D7|hemH]-[gene|7541AD7D06BC4CE30AD576562E0053CC1E25B4D6|hemY]
description
[Pubmed|1459957]
Biological materials
Mutant
BKE10140 ([gene|7541AD7D06BC4CE30AD576562E0053CC1E25B4D6|hemY]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE10140 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GTCACTCATGTTCATCGCCT, downstream forward: _UP4_TAAAACCTCCGCTTTATCGC
BKK10140 ([gene|7541AD7D06BC4CE30AD576562E0053CC1E25B4D6|hemY]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK10140 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GTCACTCATGTTCATCGCCT, downstream forward: _UP4_TAAAACCTCCGCTTTATCGC
References
Reviews
Original Publications
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Time of last update: 2025-04-07 22:57:09
Author of last update: Jstuelk