ykuQ
168
tetrahydrodipicolinate acetylase
locus
BSU_14180
Molecular weight
24.84 kDa
pI
4.68
function
biosynthesis of lysine and peptidoglycan
product
tetrahydrodipicolinate acetylase
essential
yes
ec
2.3.1.89
synonyms
ykuQ, dapH
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2171 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,488,973 1,489,683
Phenotypes of a mutant
essential [Pubmed|12682299]
The protein
Catalyzed reaction/ biological activity
(S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H2O --> CoA + L-2-acetamido-6-oxoheptanedioate (according to UniProt)
Protein family
[wiki|Transferase hexapeptide repeat family] (according to UniProt)
Structure
[PDB|3R8Y] (from ''Bacillus anthracis'', 80% identity, 96% similarity)
[AF|O34981]
Expression and Regulation
Operons
genes
[gene|716FE06124544C05CC34BA2E643B4DBD27F04998|ykuQ]-[gene|D6F1906CE8386F78F451D6B794F74DE4AD25AC9C|ykuR]-[gene|3E7E0342AA86AFCC95F5CD5BEA5B10166DCE2721|ykuS]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-B340 (ykuQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1339 NBRP B. subtilis, Japan]
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Time of last update: 2024-12-20 15:48:56
Author of last update: Jstuelk