spoIISB
168
disruption blocks sporulation after septum formation
locus
BSU_12820
Molecular weight
6.52 kDa
pI
10.79
function
sporulation
product
anti-toxin
essential
no
synonyms
spoIISB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Coordinates
1,348,442 1,348,612
Phenotypes of a mutant
sporulation efficiency is reduced by four orders of magnitude [Pubmed|11371520]
The protein
Protein family
SpoIISB antitoxin family (single member, according to UniProt)
Structure
[PDB|3O6Q] (cytoplasmic fragment of [protein|CD14C88E9976964A0D25BAA22C395A5A6951654D|spoIISA] (CSpoIISA) in complex with [protein|6C9F403D67CDC2EE66C534B0F23D973E24C9A089|spoIISB]) [Pubmed|21147767]
[AF|O34800]
Expression and Regulation
Operons
genes
[gene|CD14C88E9976964A0D25BAA22C395A5A6951654D|spoIISA]-[gene|6C9F403D67CDC2EE66C534B0F23D973E24C9A089|spoIISB]
description
[Pubmed|11371520]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
Biological materials
Mutant
1S124 ( ''spoIISB''::''tet''), [Pubmed|11371520], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S124&Search=1S124 BGSC]
BKE12820 ([gene|6C9F403D67CDC2EE66C534B0F23D973E24C9A089|spoIISB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE12820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TCTGTTTTGAAACGCACGTT, downstream forward: _UP4_TGATCACACTAAAAGGACAA
BKK12820 ([gene|6C9F403D67CDC2EE66C534B0F23D973E24C9A089|spoIISB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK12820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TCTGTTTTGAAACGCACGTT, downstream forward: _UP4_TGATCACACTAAAAGGACAA
References
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Time of last update: 2024-12-28 07:21:29
Author of last update: Melvin.boenninger