cah
168
cephalosporin C deacetylase
locus
BSU_03180
Molecular weight
35.65 kDa
pI
5.42
function
resistance to cephalosporin C
product
cephalosporin C deacetylase)
essential
no
ec
3.1.1.41
synonyms
cah
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG3458 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
342,538 343,494
The protein
Catalyzed reaction/ biological activity
cephalosporin C + H2O --> acetate + deacetylcephalosporin C + H+ (according to UniProt)
Protein family
carbohydrate esterase 7 family (single member, according to UniProt)
Structure
[PDB|1ODS] [pubmed|12842474]
[AF|P94388]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|D28190620D5B834DD7F42822B835C6FE932FD8A5|ycgK]-[gene|6BCE78F623A40B519211E79AFA1AD898318BD817|cah]-[gene|7306A55192AEB4032FD17A1BAAFF1127D511D70E|ycgL]
description
[Pubmed|22383849]
Biological materials
Mutant
BKE03180 ([gene|6BCE78F623A40B519211E79AFA1AD898318BD817|cah]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03180 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCCGATTATTCCCCTT, downstream forward: _UP4_TGATAAATGTGAAAAGCCGC
BKK03180 ([gene|6BCE78F623A40B519211E79AFA1AD898318BD817|cah]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03180 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCCGATTATTCCCCTT, downstream forward: _UP4_TGATAAATGTGAAAAGCCGC
References
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Time of last update: 2025-04-03 19:41:23
Author of last update: Melvin.boenninger