cotR

cotR
168

outer spore coat protein, lipolytic enzyme

locus
BSU_34530
Molecular weight
35.20 kDa
pI
10.2
Protein length
Gene length
function
hydrolysis of lysophospholipids
product
outer spore coat lipolytic enzyme
essential
no
synonyms
cotR, yvdO

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3621 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,544,642  3,545,604
The protein
Catalyzed reaction/ biological activity
release of myristic acid from 1-myristoly-2-lyso-sn-glycero-3-phosphocholine [Pubmed|20378985]
[wiki|Domains]
PNPLA domain (aa 7-182) (according to UniProt)
Structure
[AF|O06996]
[wiki|Localization]
outer spore coat [pubmed|28870294]
Expression and Regulation
Operons
genes
[gene|6B9B62D9687331CDC2677C78A624FA609C8F8CFC|cotR]
description
[Pubmed|22383849]
regulation
expressed late during sporulation in the mother cell ([protein|search|SigK]) [Pubmed|15699190]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|15699190], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
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[gene|6B9B62D9687331CDC2677C78A624FA609C8F8CFC|cotR]

2024-07-11 02:23:28

ghost

42

0ffdc7d2a8f6b05c7bc92631a00e2f7dd56d1b3c

E323B0E02D3DBC8A6A3EB503D9210018683D918C

Biological materials
Mutant
MGNA-B621 (yvdO::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1620 NBRP B. subtilis, Japan]
BKE34530 ([gene|6B9B62D9687331CDC2677C78A624FA609C8F8CFC|cotR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE34530 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAAGCTGATGTCTCCTTTC,  downstream forward: _UP4_TAATTATTTATTTTAAATCA
BKK34530 ([gene|6B9B62D9687331CDC2677C78A624FA609C8F8CFC|cotR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK34530 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAAGCTGATGTCTCCTTTC,  downstream forward: _UP4_TAATTATTTATTTTAAATCA
References
11737650,15699190,20378985,28870294,33596081

6B9B62D9687331CDC2677C78A624FA609C8F8CFC

Page visits: 5417

Time of last update: 2024-10-02 21:11:33

Author of last update: Jstuelk