cotR
168
outer spore coat protein, lipolytic enzyme
locus
BSU_34530
Molecular weight
35.20 kDa
pI
10.2
function
hydrolysis of lysophospholipids
product
outer spore coat lipolytic enzyme
essential
no
synonyms
cotR, yvdO
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG3621 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,544,642 3,545,604
The protein
Catalyzed reaction/ biological activity
release of myristic acid from 1-myristoly-2-lyso-sn-glycero-3-phosphocholine [Pubmed|20378985]
[wiki|Domains]
PNPLA domain (aa 7-182) (according to UniProt)
Structure
[AF|O06996]
[wiki|Localization]
outer spore coat [pubmed|28870294]
Expression and Regulation
Operons
genes
[gene|6B9B62D9687331CDC2677C78A624FA609C8F8CFC|cotR]
description
[Pubmed|22383849]
regulation
expressed late during sporulation in the mother cell ([protein|search|SigK]) [Pubmed|15699190]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|15699190], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
Biological materials
Mutant
MGNA-B621 (yvdO::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1620 NBRP B. subtilis, Japan]
BKE34530 ([gene|6B9B62D9687331CDC2677C78A624FA609C8F8CFC|cotR]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE34530 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAGCTGATGTCTCCTTTC, downstream forward: _UP4_TAATTATTTATTTTAAATCA
BKK34530 ([gene|6B9B62D9687331CDC2677C78A624FA609C8F8CFC|cotR]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK34530 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAGCTGATGTCTCCTTTC, downstream forward: _UP4_TAATTATTTATTTTAAATCA
References
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Time of last update: 2024-12-20 23:17:21
Author of last update: Jstuelk