capE
168
stimulates poly-gamma-glutamate production in the presence of zinc, also involved in extra-chromosomal DNA maintenance
locus
BSU_35870
Molecular weight
6.39 kDa
pI
6.49
function
capsule synthesis
product
unknown
essential
no
synonyms
capE, ywtC, pgsE, edmS
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Coordinates
3,697,639 3,697,806
The protein
Catalyzed reaction/ biological activity
stimulates poly-gamma-glutamate production in the presence of zinc [Pubmed|20812257]
also involved in extra-chromosomal DNA maintenance [Pubmed|23583563,21357437]
[wiki|Domains]
N-terminal membrane-anchoring domain and a C-terminal assembly accelerator-like structure [Pubmed|23583563]
Structure
[AF|P96739]
[wiki|Localization]
cell membrane [Pubmed|23583563]
Expression and Regulation
Operons
genes
[gene|86C05126ADBA22BB1771B1FA3D214B2E7A36311E|capB]-[gene|D66994D077D1382B88FF65075E44C2A31089548F|capC]-[gene|A696434A086A428D411CAF45B37CD8F82AC2503F|capA]-[gene|6B61DCE8D27776EBF942621D3AE90F410FD13F37|capE]
description
[Pubmed|11751809]
regulatory mechanism
[protein|D343D2096664A972026D911E7A17A35C7B1CD1C9|degU]: activation, [protein|D343D2096664A972026D911E7A17A35C7B1CD1C9|degU]-P, [Pubmed|19734658], in [regulon|protein:D343D2096664A972026D911E7A17A35C7B1CD1C9|degU regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|19420703], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
additional information
expression of the operon is increased in '[protein|search|motA]' or '[protein|search|motB]' mutants due to increased [protein|search|DegU] phosphorylation [PubMed|24296669]
Biological materials
Mutant
BKE35870 ([gene|6B61DCE8D27776EBF942621D3AE90F410FD13F37|capE]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE35870 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAATTTCATCTTTATCACTC, downstream forward: _UP4_TAATTCAAAAAAGAGAGTGT
BKK35870 ([gene|6B61DCE8D27776EBF942621D3AE90F410FD13F37|capE]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK35870 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAATTTCATCTTTATCACTC, downstream forward: _UP4_TAATTCAAAAAAGAGAGTGT
References
Reviews
Original Publications
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Time of last update: 2024-10-04 12:56:57
Author of last update: Jstuelk