spoVK

spoVK
168

required for spore maturation, acts as a chaperone to activate the peptidoglycan glycosyltransferase [protein|D52FDB5015B10E9B26D7FED5708457890C6EA43D|murG] during sporulation

locus
BSU_17420
Molecular weight
36.52 kDa
pI
8.82
Protein length
Gene length
function
spore maturation
product
AAA+ ATPase chaperone
essential
no
synonyms
spoVK, spoVJ

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0464 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,874,203  1,875,171
The protein
Protein family
cbxX/cfxQ family (single member, according to UniProt)
Structure
[PDB|3ZUH] (from Rhodobacter sphaeroides, 41% identity) [pubmed|22048315]
[AF|P27643]
Expression and Regulation
Operons
genes
[gene|69D4685E435B472A3E87E312ECA77553631687E4|spoVK]
description
[Pubmed|1787791]
regulation
expressed during sporulation in the mother cell ([protein|search|SigE], [protein|search|SigK]) [Pubmed|15699190,1787791]
regulatory mechanism
[protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]: activation, [Pubmed|15383836], in [regulon|protein:90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID regulon]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15699190,1787791], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|1787791], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
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[gene|69D4685E435B472A3E87E312ECA77553631687E4|spoVK]

2024-10-10 17:34:09

ghost

43

514217a999ec57d4a9e0cdf976b1ebb4cdfdae0d

8696C5A04C3660A4EF40EDDA10FAE063D55B2315

Biological materials
Mutant
1S99 ( ''spoVK''::''erm''), [Pubmed|1732196], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S99&Search=1S99 BGSC]
BKE17420 ([gene|69D4685E435B472A3E87E312ECA77553631687E4|spoVK]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE17420 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCTTCACCTCTCTGTTCT,  downstream forward: _UP4_TAGACCTCTCAGTTTTTGAG
BKK17420 ([gene|69D4685E435B472A3E87E312ECA77553631687E4|spoVK]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK17420 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCTTCACCTCTCTGTTCT,  downstream forward: _UP4_TAGACCTCTCAGTTTTTGAG
References
Reviews
35638784
Original Publications
1787791,1732196,2514336,15383836,22048315,37986874

69D4685E435B472A3E87E312ECA77553631687E4

Page visits: 2574

Time of last update: 2024-10-11 20:06:56

Author of last update: Jstuelk