csoR
168
transcription repressor of [gene|18506FB74F6BB9278F22EB7DCDA3CF72575CC32A|copZ]-[gene|727024F7B1AC19676ED4B516CF46A47B1328310B|copA]
locus
BSU_33520
Molecular weight
11.34 kDa
pI
7.3
function
control of copper homeostasis
product
transcription repressor
essential
no
synonyms
csoR, yvgZ
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1937 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,443,896 3,444,201
The protein
Protein family
CsoR family (single member, according to UniProt)
Structure
[PDB|4M1P] (from Geobacillus thermodenitrificans, 59% identity) [pubmed|24831014]
[AF|O32222]
Effectors of protein activity
Cu(I) ions cause release of CsoR from its operator sites
Expression and Regulation
Operons
genes
[gene|6977F18870004AD236539D9409255815E6BE9241|csoR]-[gene|18506FB74F6BB9278F22EB7DCDA3CF72575CC32A|copZ]-[gene|727024F7B1AC19676ED4B516CF46A47B1328310B|copA]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-B604 (yvgZ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1603 NBRP B. subtilis, Japan]
BKE33520 ([gene|6977F18870004AD236539D9409255815E6BE9241|csoR]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33520 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCGTACACCTCTGTTTA, downstream forward: _UP4_TAAAGCGTTTTTTATTGTAA
BKK33520 ([gene|6977F18870004AD236539D9409255815E6BE9241|csoR]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33520 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCGTACACCTCTGTTTA, downstream forward: _UP4_TAAAGCGTTTTTTATTGTAA
labs
[wiki|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]
[wiki|Mohamed Marahiel], Marburg University, Germany [http://www.uni-marburg.de/fb15/fachgebiete/bio/marahiel?language_sync=1 homepage]
References
Reviews
Original Publications
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Time of last update: 2024-10-07 15:45:38
Author of last update: Melvin.boenninger