ytcC
168
sporulation protein, similar to lipopolysaccharide N-acetylglucosaminyltransferase
locus
BSU_30880
Molecular weight
46.00 kDa
pI
9.59
function
lipopolysaccharide biosynthesis
product
sporulation protein
essential
no
synonyms
ytcC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0438 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,157,961 3,159,184
The protein
Protein family
[wiki|glycosyltransferase 1 family] (according to UniProt)
[wiki|Glycosyltransferase 4 subfamily] (according to UniProt)
Structure
[AF|O34413]
Paralogous protein(s)
[protein|2C17028E7DC755FFC190397AC6509E383C4DF99A|cotSA]
Expression and Regulation
Operons
genes
[gene|59024C05AA0106719C81E45E3B060A6F710B2690|ytcA]-[gene|A51B5F9F86D2F7B690712B9EC181B1C07B312E02|ytcB]-[gene|6911DFB27F6A23F3775DAC5C289EFA163FBD1E56|ytcC]
description
[Pubmed|22383849]
regulation
expressed late during sporulation in the mother cell ([protein|6FAD8804AA32B84819DDE57C0AF63F208FB9FFD1|sigKC], [wiki|GerE]) [Pubmed|26577401,15699190,12480901]
regulatory mechanism
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: repression, [Pubmed|26577401], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|22383849,15699190,12480901], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
additional information
translation is likely to require [protein|3054CD45713BBD69C2A528DE24AF6AF37175FD9D|efp] due to the presence of several consecutive proline residues [PubMed|23239624,23239623]
Biological materials
Mutant
MGNA-A278 (ytcC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/278 NBRP B. subtilis, Japan]
BKE30880 ([gene|6911DFB27F6A23F3775DAC5C289EFA163FBD1E56|ytcC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE30880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTTATTCCCCCTGATA, downstream forward: _UP4_TAAAACCTACAGCTCGTGTT
BKK30880 ([gene|6911DFB27F6A23F3775DAC5C289EFA163FBD1E56|ytcC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK30880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTTATTCCCCCTGATA, downstream forward: _UP4_TAAAACCTACAGCTCGTGTT
References
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Time of last update: 2024-12-31 05:09:31
Author of last update: Melvin.boenninger