ytzG
168
similar to 16S pseudouridylate synthase
locus
BSU_30035
Molecular weight
27.00 kDa
pI
5.619
function
16S rRNA modification
product
putative 16S pseudouridylate synthase
essential
no
ec
5.4.99.19
synonyms
ytzG, ytzF
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1187 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,072,743 3,073,462
The protein
Catalyzed reaction/ biological activity
uridine516 in 16S rRNA --> a pseudouridine516 in 16S rRNA (according to E. coli RsuA)
Protein family
[wiki|S4 RNA-binding domain] superfamily (according to http://www.ebi.ac.uk/interpro/entry/IPR036986 Interpro)
pseudouridine synthase RsuA family (with [protein|5CD1E266B0EC82546A2AF19A05490DD4D04F812C|rluB], according to UniProt)
[wiki|Domains]
[wiki|S4 RNA-binding domain] (aa 1-65) (according to UniProt)
Structure
[PDB|1KSK] (RsuA from E. coli, 40% identical) [pubmed|11953756]
[AF|O32068]
Expression and Regulation
Operons
genes
[gene|0AFFB4B715CCE6B1C53BBB7F890EFB3126CB466E|murJ]-[gene|69052B24B577ABA4B20E610F679154DC97EFD8DE|ytzG]
description
[Pubmed|22383849]
Biological materials
Mutant
BKE30035 ([gene|69052B24B577ABA4B20E610F679154DC97EFD8DE|ytzG]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE30035 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCCCAATCTCTCCTTTA, downstream forward: _UP4_TGACAAAAACCCCGCATACC
BKK30035 ([gene|69052B24B577ABA4B20E610F679154DC97EFD8DE|ytzG]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK30035 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCCCAATCTCTCCTTTA, downstream forward: _UP4_TGACAAAAACCCCGCATACC
References
Research papers
Page visits: 1992
Time of last update: 2024-12-20 18:29:14
Author of last update: Melvin.boenninger