yflN
168
similar to metallo-beta-lactamase
locus
BSU_07620
Molecular weight
28.68 kDa
pI
5.07
function
unknown
product
unknown
essential
no
synonyms
yflN
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0491 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
835,740 836,534
The protein
Protein family
[wiki|metallo-beta-lactamase superfamily] (according to UniProt)
Structure
[PDB|4AWY] (from Pseudomonas aeruginosa, 25% identity) [pubmed|22664968]
[AF|O34409]
Expression and Regulation
Operons
genes
[gene|C0DED68802EF78D2BC16507234AAC3B60D236E68|citM]-[gene|66B9809A77AB15E5C8C8E5A8E26752771AF55E3A|yflN]
description
[Pubmed|10972810]
regulation
induced by citrate ([protein|search|CitT]) [Pubmed|10972810]
regulatory mechanism
[protein|1345FBA88CB55E0E897FEC8DA4D829B85A8393BB|citT]: activation, [Pubmed|10972810], in [regulon|protein:1345FBA88CB55E0E897FEC8DA4D829B85A8393BB|citT regulon]
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|22900538,10972810], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|10972810], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
MGNA-C253 (yflN::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2251 NBRP B. subtilis, Japan]
BKE07620 ([gene|66B9809A77AB15E5C8C8E5A8E26752771AF55E3A|yflN]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE07620 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAATGACACCTCCGGAAT, downstream forward: _UP4_TGACACCCGCACCACGCGGG
BKK07620 ([gene|66B9809A77AB15E5C8C8E5A8E26752771AF55E3A|yflN]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK07620 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAATGACACCTCCGGAAT, downstream forward: _UP4_TGACACCCGCACCACGCGGG
References
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Time of last update: 2024-12-21 21:04:10
Author of last update: Jstuelk