spoVID
168
developmental checkpoint, co-ordinates spore cortex and coat assembly, spore coat morphogenetic protein, non-competitive hub during spore encasement, promotes encasement of the spore
locus
BSU_28110
Molecular weight
64.80 kDa
pI
4
function
spore coat assembly
product
spore coat morphogenetic protein
essential
no
synonyms
spoVID
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG5846 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,871,022 2,872,749
Phenotypes of a mutant
accumulation of [protein|CEBEC9CECCF445C40D793E61A2CD23175631A473|safA] and [protein|825AD8D4315A85CD384F9AF6AD894E38E57C88F7|cotE] and their dependent proteins at the mother cell proximal spore pole [pubmed|30168214]
The protein
Catalyzed reaction/ biological activity
measures the successful polymerization of the coat basement layer [pubmed|35065768]
ensures orchestrated assembly of the spore envelope [pubmed|35065768]
[wiki|Domains]
contains a N-acetylglucosamine-polymer-binding [wiki|LysM domain] (aa 523-567) [Pubmed|18430080]
[wiki|LysM domain] (aa 523-567) (according to UniProt)
Structure
[AF|P37963]
[wiki|Localization]
spore coat (basement), localization depends on [protein|A25C1530DA7BB007A288E525404E9F775E219FE8|spoIVA] [Pubmed|22773792,22171814]
Expression and Regulation
Operons
genes
[gene|6698BB092E03BEF48AFD0CBF565410109CD1ABB5|spoVID]-[gene|D1EAEC9C88EDDD8FB2E7E315DE28A7A54AAAB4D2|ysxE]
description
[Pubmed|15699190,8449878]
regulation
expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|15699190,8449878]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15699190,8449878], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
Biological materials
Mutant
1A639 ( ''spoVID''::''erm''), [Pubmed|3015878], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A639&Search=1A639 BGSC]
1S127 ( ''spoVID''::''erm''), [Pubmed|16751597], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S127&Search=1S127 BGSC]
BKE28110 ([gene|6698BB092E03BEF48AFD0CBF565410109CD1ABB5|spoVID]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE28110 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAGTTCATATCCTCCTTTC, downstream forward: _UP4_TAAACCGTAAGTGATCGGAA
BKK28110 ([gene|6698BB092E03BEF48AFD0CBF565410109CD1ABB5|spoVID]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK28110 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAGTTCATATCCTCCTTTC, downstream forward: _UP4_TAAACCGTAAGTGATCGGAA
labs
[wiki|Adriano Henriques], Lisbon, Portugal [http://www.itqb.unl.pt/research/biology/microbial-development homepage]
[wiki|Charles Moran], Emory University, NC, USA [http://www.microbiology.emory.edu/moran_c.html homepage]
References
Reviews
Original Publications
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Time of last update: 2024-12-30 23:41:41
Author of last update: Jstuelk