kre

kre
168

[protein|08CFA2C72931A75532D4289BC1D18A826DE9F9CA|comK] repressor, stimulates degradation of the [gene|search|comK ]mRNA

locus
BSU_14020
Molecular weight
17.75 kDa
pI
10.17
Protein length
Gene length
function
control of [protein|search|ComK ]accumulation and of bistable competence gene expression
product
[protein|search|ComK ]repressor
essential
no
synonyms
kre, ykyB

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
1,474,560  1,475,024
The protein
Catalyzed reaction/ biological activity
stimulates [protein|08CFA2C72931A75532D4289BC1D18A826DE9F9CA|comK] mRNA degradation [Pubmed|26110430]
controls stability of several mRNAs (see [wiki|Kre regulon]) [Pubmed|26110430]
Structure
[AF|P42430]
[wiki|Localization]
cytoplasm [Pubmed|26110430]
Expression and Regulation
Operons
genes
[gene|65E2F7197D46F5C884CC96018EE4F3EEE94FFA18|kre]
description
[Pubmed|8169223]
regulation
repressed in competent cells ([wiki|ComK]) [Pubmed|26110430]
regulatory mechanism
[protein|08CFA2C72931A75532D4289BC1D18A826DE9F9CA|comK]: repression, [Pubmed|26110430], in [regulon|protein:08CFA2C72931A75532D4289BC1D18A826DE9F9CA|comK regulon]
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[gene|65E2F7197D46F5C884CC96018EE4F3EEE94FFA18|kre]

2024-08-04 19:29:26

ghost

44

ad728fe670e47a4ecd520fc68fedc2951eabc193

1C0577476FBB6BCEC41381B6F6677BD2DA922722

Biological materials
Mutant
MGNA-A764 (ykyB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/764 NBRP B. subtilis, Japan]
PG479 (ykyB::erm), available in [wiki|Leendert Hamoen]'s and [wiki|Jörg Stülke]'s labs [Pubmed|26110430]
GP2533 ([gene|65E2F7197D46F5C884CC96018EE4F3EEE94FFA18|kre]::''erm''), available in [wiki|Jörg Stülke]'s lab
BKE14020 ([gene|65E2F7197D46F5C884CC96018EE4F3EEE94FFA18|kre]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE14020 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTATTTCTCTCCTTTGCT,  downstream forward: _UP4_TAAAATAAAAACAGCCGTGC
BKK14020 ([gene|65E2F7197D46F5C884CC96018EE4F3EEE94FFA18|kre]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK14020 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTATTTCTCTCCTTTGCT,  downstream forward: _UP4_TAAAATAAAAACAGCCGTGC
References
Reviews
26110607
Original Publications
8169223,26110430

65E2F7197D46F5C884CC96018EE4F3EEE94FFA18

Page visits: 3450

Time of last update: 2024-10-07 13:23:20

Author of last update: Jstuelk