dgkA

dgkA
168

undecaprenol kinase

locus
BSU_25310
Molecular weight
12.40 kDa
pI
7.13
Protein length
Gene length
function
cell wall biosynthesis
product
undecaprenol kinase
essential
no
ec
2.7.1.107
synonyms
dgkA, yqxF

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0818 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,611,456  2,611,827
Phenotypes of a mutant
inactivation of ''[gene|65D3306FE372FF730DD6C62B841AA80CA30AEA43|dgkA]'' reduces sporulation efficiency to 33.7% that of wild type cells [Pubmed|26735940]
The protein
Catalyzed reaction/ biological activity
ATP + di-trans,octa-cis-undecaprenol --> ADP + di-trans,octa-cis-undecaprenyl phosphate + H+ (according to UniProt)
Protein family
Bacterial diacylglycerol kinase family (single member, according to UniProt)
Structure
[AF|P19638]
[wiki|Localization]
cell membrane at the septum [Pubmed|15743965]
Biological materials
Mutant
BKE25310 ([gene|65D3306FE372FF730DD6C62B841AA80CA30AEA43|dgkA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE25310 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TTTGAAGAATCGATTCAGCT,  downstream forward: _UP4_TAATGGCTGAAAATTCTTAC
BKK25310 ([gene|65D3306FE372FF730DD6C62B841AA80CA30AEA43|dgkA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK25310 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TTTGAAGAATCGATTCAGCT,  downstream forward: _UP4_TAATGGCTGAAAATTCTTAC
References
12923107,17535816,15743965,26735940,29259598

65D3306FE372FF730DD6C62B841AA80CA30AEA43

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Time of last update: 2024-10-09 04:25:32

Author of last update: Melvin.boenninger