pbuO
168
similar to hypoxanthine/guanine permease [protein|41DDD3AAFE89D0F52AB5ABD08CEE30A1767FFD7A|pbuG]
locus
BSU_29990
Molecular weight
45.26 kDa
pI
7.48
function
unknown
product
unknown
essential
no
synonyms
pbuO, ytiP
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2252 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,068,908 3,070,206
The protein
Protein family
[wiki|xanthine/uracil permease family] (according to UniProt)
Structure
[AF|O34978]
Paralogous protein(s)
[protein|41DDD3AAFE89D0F52AB5ABD08CEE30A1767FFD7A|pbuG]
Expression and Regulation
Operons
genes
[gene|62AC66725C55B9E5FBBEB4EC43A88F7081B74D5C|pbuO]
description
[Pubmed|9387221]
regulation
repressed in the presence of purine nucleotides ([protein|search|PurR]) [Pubmed|11591660,2536750]
regulatory mechanism
[protein|A8C82F5825DE0921DA6B4ACDE0CC31EC7749273C|purR]: repression, (molecular inducer: PRPP) [Pubmed|11591660,2536750], in [regulon|protein:A8C82F5825DE0921DA6B4ACDE0CC31EC7749273C|purR regulon]
Biological materials
Mutant
MGNA-A819 (ytiP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/819 NBRP B. subtilis, Japan]
BKE29990 ([gene|62AC66725C55B9E5FBBEB4EC43A88F7081B74D5C|pbuO]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE29990 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGTATCCTCCAATTACG, downstream forward: _UP4_TAAGGATAGACCAAAAAACC
BKK29990 ([gene|62AC66725C55B9E5FBBEB4EC43A88F7081B74D5C|pbuO]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK29990 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGTATCCTCCAATTACG, downstream forward: _UP4_TAAGGATAGACCAAAAAACC
References
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Time of last update: 2024-12-22 02:41:12
Author of last update: Melvin.boenninger