ycbL
168
two-component response regulator ([wiki|OmpR family])
locus
BSU_02550
Molecular weight
25.66 kDa
pI
4.92
function
unknown
product
two-component response regulator ([wiki|OmpR family])
essential
no
synonyms
ycbL
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0745 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
278,377 279,057
The protein
Protein family
[wiki|OmpR family] of two-component response regulators
[wiki|Domains]
[wiki|Response regulatory domain] (aa 1-112) (according to UniProt)
Structure
[PDB|2OQR] (RegX3 from Mycobacterium tuberculosis, 38% identity) [pubmed|17942407]
[AF|P42244]
Modification
phosphorylation by [protein|348F81B6ECB6FFBEC092A672FF5F40FE86918872|ycbM] ( on an aspartate residue, putative)
Effectors of protein activity
activity is controlled by [protein|348F81B6ECB6FFBEC092A672FF5F40FE86918872|ycbM]-dependent phosphorylation (putative)
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|60DA46B02BB5F71337AF5F34921E2E68EC062EC7|ycbL]-[gene|348F81B6ECB6FFBEC092A672FF5F40FE86918872|ycbM]-[gene|FE7AC936BE959D745FBB6A88EAD64408C7177125|ycbN]-[gene|621FA6E2A76BB74F9051FBDB6857ED56F65BAB15|ycbO]
description
[pubmed|22383849]
Biological materials
Mutant
MGNA-C034 (ycbL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2032 NBRP B. subtilis, Japan]
BKE02550 ([gene|60DA46B02BB5F71337AF5F34921E2E68EC062EC7|ycbL]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE02550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATATGCGCTGCATCTCCT, downstream forward: _UP4_GGTTATAAATTAGGAGAGTT
BKK02550 ([gene|60DA46B02BB5F71337AF5F34921E2E68EC062EC7|ycbL]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK02550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATATGCGCTGCATCTCCT, downstream forward: _UP4_GGTTATAAATTAGGAGAGTT
References
Page visits: 2062
Time of last update: 2024-12-19 10:35:42
Author of last update: Melvin.boenninger