ycbL

ycbL
168

two-component response regulator ([wiki|OmpR family])

locus
BSU_02550
Molecular weight
25.66 kDa
pI
4.92
Protein length
Gene length
function
unknown
product
two-component response regulator ([wiki|OmpR family])
essential
no
synonyms
ycbL

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0745 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
278,377  279,057
The protein
Protein family
[wiki|OmpR family] of two-component response regulators
[wiki|Domains]
[wiki|Response regulatory domain] (aa 1-112) (according to UniProt)
Structure
[PDB|2OQR] (RegX3 from Mycobacterium tuberculosis, 38% identity) [pubmed|17942407]
[AF|P42244]
Modification
phosphorylation by [protein|348F81B6ECB6FFBEC092A672FF5F40FE86918872|ycbM] ( on an aspartate residue, putative)
Effectors of protein activity
activity is controlled by [protein|348F81B6ECB6FFBEC092A672FF5F40FE86918872|ycbM]-dependent phosphorylation (putative)
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|60DA46B02BB5F71337AF5F34921E2E68EC062EC7|ycbL]-[gene|348F81B6ECB6FFBEC092A672FF5F40FE86918872|ycbM]-[gene|FE7AC936BE959D745FBB6A88EAD64408C7177125|ycbN]-[gene|621FA6E2A76BB74F9051FBDB6857ED56F65BAB15|ycbO]
description
[pubmed|22383849]
Open in new tab

[gene|60DA46B02BB5F71337AF5F34921E2E68EC062EC7|ycbL]→[gene|621FA6E2A76BB74F9051FBDB6857ED56F65BAB15|ycbO]

2024-09-14 11:16:27

Jstuelk

62

77090242fa94fd81070f7200512e38f969f10d55

C42DE0C164AE1418C323B42BA4174D5584CA1EA2

Biological materials
Mutant
MGNA-C034 (ycbL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2032 NBRP B. subtilis, Japan]
BKE02550 ([gene|60DA46B02BB5F71337AF5F34921E2E68EC062EC7|ycbL]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE02550 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAATATGCGCTGCATCTCCT,  downstream forward: _UP4_GGTTATAAATTAGGAGAGTT
BKK02550 ([gene|60DA46B02BB5F71337AF5F34921E2E68EC062EC7|ycbL]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK02550 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAATATGCGCTGCATCTCCT,  downstream forward: _UP4_GGTTATAAATTAGGAGAGTT
References
10094672,23504016,17942407

60DA46B02BB5F71337AF5F34921E2E68EC062EC7

Page visits: 1961

Time of last update: 2024-10-07 13:48:38

Author of last update: Melvin.boenninger