yjcK
168
similar to ribosomal-protein-alanine N-acetyltransferase
locus
BSU_11890
Molecular weight
20.78 kDa
pI
5.46
function
unknown
product
unknown
essential
no
ec
2.3.1.128
synonyms
yjcK
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1670 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,260,811 1,261,356
The protein
Catalyzed reaction/ biological activity
acetyl-CoA + N-terminal L-alanyl-[ribosomal protein uS5] --> CoA + H+ + N-terminal Nα-acetyl-L-alanyl-[ribosomal protein uS5] (according to UniProt)
Protein family
[wiki|Acetyltransferase family] (according to UniProt)
[wiki|Domains]
[wiki|N-acetyltransferase domain] (aa 7-172) (according to UniProt)
Structure
[PDB|3IGR] (from Vibrio fischeri, 35% identity)
[AF|O31633]
Paralogous protein(s)
[protein|BFDAB855DC76A78C100DC5E5FB81F73069F5F93F|ydaF]
[protein|F92B7EC7A00BF295666D68613932D239F92C7347|ykkB], (30.3%)
[wiki|Localization]
cytoplasm (Homogeneous) [Pubmed|16479537]
Expression and Regulation
Operons
genes
[gene|470824F73C8C9CF0519C1E536DBF19D8A93723CE|yjcL]-[gene|6072A6EF0766F3D1B1616A20CDC36CCDC6CBDA71|yjcK]
description
[Pubmed|22383849]
expression
expression is increased upon depletion of depletion of tRNA maturation factors [gene|57A79AAF00243B5E058FA901D43AA7B55CA33F63|rnpB] or [gene|C40C5D35ED53D343C8200248FCCB010BAB388054|rnz] [pubmed|36840557]
Biological materials
Mutant
MGNA-B257 (yjcK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1256 NBRP B. subtilis, Japan]
GP1246 (''yjcK''::''cat''), available in [wiki|Jörg Stülke]'s lab
GP1255 (''[gene|17C3F56CE859BCD7A282C144C46CC92D3506ABF6|acuA]''::''kan'' ''[gene|6072A6EF0766F3D1B1616A20CDC36CCDC6CBDA71|yjcK]''::''cat'' ''[gene|18FA5EFCD78C74296F9E52A64DA4A9D635944528|ynaD]''::''spec'' ''[gene|4A8360E50ADBA4CC859A64A72EBC0A07F70A1764|yoaA]''::''tet''), available in [wiki|Jörg Stülke]'s lab
BP139 (''[gene|470824F73C8C9CF0519C1E536DBF19D8A93723CE|yjcL]-[gene|6072A6EF0766F3D1B1616A20CDC36CCDC6CBDA71|yjcK]''::''ermC''), available in [wiki|Fabian Commichau]'s lab
BKE11890 ([gene|6072A6EF0766F3D1B1616A20CDC36CCDC6CBDA71|yjcK]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE11890 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATAGTGATCTCTCCGTT, downstream forward: _UP4_TAATAAAAGAAGCCGGACTA
BKK11890 ([gene|6072A6EF0766F3D1B1616A20CDC36CCDC6CBDA71|yjcK]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK11890 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATAGTGATCTCTCCGTT, downstream forward: _UP4_TAATAAAAGAAGCCGGACTA
References
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Time of last update: 2024-12-21 08:16:03
Author of last update: Jstuelk