yhxC
168
similar to alcohol dehydrogenase
locus
BSU_10400
Molecular weight
30.69 kDa
pI
7.26
function
unknown
product
unknown
essential
no
synonyms
yhxC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1028 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,115,698 1,116,555
Phenotypes of a mutant
reduced transfomation efficiency [pubmed|32249531]
The protein
Protein family
[wiki|Short-chain dehydrogenases/reductases (SDR) family] (according to UniProt)
Structure
[PDB|3I30] (from ''Bacillus Anthracis Str. 'amesAncestor''', 68% identity)
[AF|P40397]
Paralogous protein(s)
[protein|0DD474462720CAEE2AE17017BD7CA385238EBC6F|yxbG], [protein|20A7DBA142F3BF8DCAD9732BD908CE8CC79AA993|bacC], [protein|248F0805272FED9B38ECBB31E2872BC9EC163CE0|ymfI], [protein|439B468A13137000FB42E9389391CB4986FFED84|fabG]
[protein|6BA346D8A7B496F9618AFAB4FEEF4BD1A41D2C7E|yoxD], (31,5%)
[protein|739B228743BC1FE9E6888E999BC0E4F615E36F9E|yhxD], (45,2%),
[protein|B6FF689E65906186F3576B378650D713DB84EDDA|ycdF], (32,4%),
[protein|CA4597C6253CCF7D7954686A30AF041808BDF8E5|gdh], (34,1%)
[protein|CE990D33A12C50D22506A52E0099F7D97A762D4E|fadH], (31.9%)
[protein|D9D1FCBFC62F93CAA34DF61A784406F4E9EE6768|yjdA], (32,9%)
[protein|EAEEA4DD9641919830A81185333A2610B964D37C|yhdF], (62.3%)
[protein|FBBDE1E058223D5E8CEB07CAA50940A329C809E4|kduD], (33,6%)
[protein|3161519994609DA9360ED6E073E4A4C8C6210EFB|ydaD], (63,5%)
[protein|4DEFC2998464BF8327578C36A13A10DD277F991E|ykvO], (32,5%)
[protein|0DD474462720CAEE2AE17017BD7CA385238EBC6F|yxbG] (36,2%), [protein|439B468A13137000FB42E9389391CB4986FFED84|fabG] (34.7%), [protein|B6FF689E65906186F3576B378650D713DB84EDDA|ycdF] (32,4%),
[protein|CA4597C6253CCF7D7954686A30AF041808BDF8E5|gdh] (34,1%), [protein|20A7DBA142F3BF8DCAD9732BD908CE8CC79AA993|bacC] (36.0%), [protein|248F0805272FED9B38ECBB31E2872BC9EC163CE0|ymfI](30.3%), [protein|CE990D33A12C50D22506A52E0099F7D97A762D4E|fadH] (31.9%), [protein|FBBDE1E058223D5E8CEB07CAA50940A329C809E4|kduD](33,6%), [protein|4DEFC2998464BF8327578C36A13A10DD277F991E|ykvO] (35.2%), [protein|6BA346D8A7B496F9618AFAB4FEEF4BD1A41D2C7E|yoxD] (31,5%), [protein|D9D1FCBFC62F93CAA34DF61A784406F4E9EE6768|yjdA] (32,9%)
Expression and Regulation
Operons
genes
[gene|6047F2493FCE3D2A9BDB1AD88E5926ECEED81036|yhxC]
description
[Pubmed|8196543]
regulation
expressed during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|15699190,12480901]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15699190,12480901], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
Biological materials
Mutant
MGNA-A718 (yhxC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/718 NBRP B. subtilis, Japan]
BKE10400 ([gene|6047F2493FCE3D2A9BDB1AD88E5926ECEED81036|yhxC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE10400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGAAATCACTCCTTTTC, downstream forward: _UP4_TAATAAAAAGCCAATCCTTG
BKK10400 ([gene|6047F2493FCE3D2A9BDB1AD88E5926ECEED81036|yhxC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK10400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGAAATCACTCCTTTTC, downstream forward: _UP4_TAATAAAAAGCCAATCCTTG
References
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Time of last update: 2024-10-04 10:21:12
Author of last update: Jstuelk