spoIIIAA
168
AAA protease, required for [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG] activation
locus
BSU_24430
Molecular weight
34.14 kDa
pI
8.18
function
activation of [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]
product
AAA protease
essential
no
synonyms
spoIIIAA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG3854 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,536,690 2,537,613
The protein
Structure
[AF|Q01367]
[wiki|Localization]
membrane protein [Pubmed|18485064]
Expression and Regulation
Operons
genes
[gene|70408C17CF8681998F7FD933D4BFF71D052626D9|yqhV]-[gene|5FE74F270B28A404BFE0DAA4EB243009EEDEACF0|spoIIIAA]-[gene|D20198968665D3726839B2DC7F0638614319B853|spoIIIAB]-[gene|5CDBE6E299C7E6606D3C52E509CFED6F41F1E3F8|spoIIIAC]-[gene|576E36DA79F1ED097D649C35C5B59622FF1CFEF3|spoIIIAD]-[gene|9D4AE9AE191BFA82791549852782DC1B959A6897|spoIIIAE]-[gene|8A8C67AB955660FA41039B45F60A5B9F7B57704E|spoIIIAF]-[gene|5456B0C27EAE89F5B9E750D65E1E3C6EDA27C9FA|spoIIIAG]-[gene|00BDD4E3370DB3A9F4D75FE265A2A8DF05185CCC|spoIIIAH]
description
[Pubmed|1766372]
regulation
both promoters: expressed during sporulation in the mother cell ([protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]) [Pubmed|18485064], switched off by [wiki|SpoIIID] [Pubmed|15383836]
regulatory mechanism
[protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]: repression, [Pubmed|15383836], in [regulon|protein:90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID regulon]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15699190,18485064], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
genes
[gene|5FE74F270B28A404BFE0DAA4EB243009EEDEACF0|spoIIIAA]-[gene|D20198968665D3726839B2DC7F0638614319B853|spoIIIAB]-[gene|5CDBE6E299C7E6606D3C52E509CFED6F41F1E3F8|spoIIIAC]-[gene|576E36DA79F1ED097D649C35C5B59622FF1CFEF3|spoIIIAD]-[gene|9D4AE9AE191BFA82791549852782DC1B959A6897|spoIIIAE]-[gene|8A8C67AB955660FA41039B45F60A5B9F7B57704E|spoIIIAF]-[gene|5456B0C27EAE89F5B9E750D65E1E3C6EDA27C9FA|spoIIIAG]-[gene|00BDD4E3370DB3A9F4D75FE265A2A8DF05185CCC|spoIIIAH]
description
[Pubmed|18485064]
regulation
both promoters: expressed during sporulation in the mother cell ([protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]) [Pubmed|18485064], switched off by [wiki|SpoIIID] [Pubmed|15383836]
Biological materials
Mutant
BKE24430 ([gene|5FE74F270B28A404BFE0DAA4EB243009EEDEACF0|spoIIIAA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE24430 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAACAGAGCCTCCTCCTTTC , downstream forward: _UP4_AATGTGCTGTCTAGGACGACG
BKK24430 ([gene|5FE74F270B28A404BFE0DAA4EB243009EEDEACF0|spoIIIAA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK24430 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAACAGAGCCTCCTCCTTTC , downstream forward: _UP4_AATGTGCTGTCTAGGACGACG
References
Reviews
Original Publications
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Time of last update: 2024-10-12 12:43:51
Author of last update: Jstuelk