aroH
168
chorismate mutase (isozymes 1 and 2)
locus
BSU_22690
Molecular weight
14.38 kDa
pI
5.52
function
biosynthesis of aromatic amino acids
product
chorismate mutase (isozymes 1 and 2)
essential
no
ec
5.4.99.5
synonyms
aroH
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4401 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,377,632 2,378,015
The protein
Catalyzed reaction/ biological activity
Chorismate --> prephenate (according to UniProt)
[wiki|Domains]
Chorismate mutase aroH-type domain (aa 3-121) (according to UniProt)
Structure
[PDB|2CHT] (complex with a transition state analog) [pubmed|8378335]
[PDB|1DBF]
[AF|P19080]
Expression and Regulation
Operons
genes
[gene|1217807AE3AE3A654BA0DD4AF5ADF1CEE62632B6|cheR]-[gene|9712D0E655289C97315314BDEE1A0DF2ED2ADCA2|aroF]-[gene|58B782C1F7931F8671161455E65E3D5C72B0BB9C|aroB]-[gene|5C2F7F9F5FCBFEDF77AC41725EFDA0FAF0FC3BC1|aroH]
description
[pubmed|22383849]
genes
[gene|9712D0E655289C97315314BDEE1A0DF2ED2ADCA2|aroF]-[gene|58B782C1F7931F8671161455E65E3D5C72B0BB9C|aroB]-[gene|5C2F7F9F5FCBFEDF77AC41725EFDA0FAF0FC3BC1|aroH]
description
[pubmed|21815947]
Biological materials
Mutant
BKE22690 ([gene|5C2F7F9F5FCBFEDF77AC41725EFDA0FAF0FC3BC1|aroH]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE22690 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGCTCCGCGAATTCCGCGAA, downstream forward: _UP4_TAATACGATAAGAACAGCTT
BKK22690 ([gene|5C2F7F9F5FCBFEDF77AC41725EFDA0FAF0FC3BC1|aroH]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK22690 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGCTCCGCGAATTCCGCGAA, downstream forward: _UP4_TAATACGATAAGAACAGCTT
References
Reviews
Original Publications
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Time of last update: 2024-12-02 12:48:49
Author of last update: Jstuelk