opuD

opuD
168

glycine betaine and arsenobetaine transporter

locus
BSU_30070
Molecular weight
55.95 kDa
pI
9.51
Protein length
Gene length
function
compatible solute transport
product
glycine betaine transporter
essential
no
synonyms
opuD, ytfQ

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1292 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,076,818  3,078,356
The protein
Catalyzed reaction/ biological activity
uptake of glycine betaine and arsenobetaine [pubmed|29159878]
Protein family
BCCT transporter (TC 2.A.15) family (single member, according to UniProt)
Structure
[PDB|4AIN] (BetP from Corynebacterium glutamicum, 44% identity) [pubmed|22940865]
[AF|P54417]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|86274AAF9E0D0882F1AD9D4A528BECB013B71C38|ytfP]-[gene|597B517CA4277E33153F80919213BFF7BE495563|opuD]
description
[Pubmed|22383849]
regulation
induced by cold stress [Pubmed|21296969]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|21296969], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|21296969], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
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[gene|86274AAF9E0D0882F1AD9D4A528BECB013B71C38|ytfP]→[gene|597B517CA4277E33153F80919213BFF7BE495563|opuD]

2024-09-28 12:30:04

Jstuelk

66

54ac002a96f5c23f598dcd5b74469ec51cb45455

23505BA4325B426B279B8F15BB2AC15A466E33D8

Biological materials
Mutant
MGNA-A815 (opuD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/815 NBRP B. subtilis, Japan]
1A1052 ( ''opuD''::''kan''), [Pubmed|21296969], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A1052&Search=1A1052 BGSC]
1A1053 ( ''opuD''::''kan''), [Pubmed|21296969], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A1053&Search=1A1053 BGSC]
1A1054 ( ''opuD''::''kan''), [Pubmed|21296969], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A1054&Search=1A1054 BGSC]
1A1055 ( ''opuD''::''kan''), [Pubmed|21296969], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A1055&Search=1A1055 BGSC]
BKE30070 ([gene|597B517CA4277E33153F80919213BFF7BE495563|opuD]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE30070 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTCTCACCCTCTAATTT,  downstream forward: _UP4_TAACAAAAAAGATCTTTCCG
BKK30070 ([gene|597B517CA4277E33153F80919213BFF7BE495563|opuD]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK30070 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTCTCACCCTCTAATTT,  downstream forward: _UP4_TAACAAAAAAGATCTTTCCG
labs
[wiki|Erhard Bremer], University of Marburg, Germany [http://www.uni-marburg.de/fb17/fachgebiete/mikrobio/molmibi homepage]
References
Reviews
27935846
Original Publications
8752321,21296969,8752321,29159878,22940865

597B517CA4277E33153F80919213BFF7BE495563

Page visits: 5931

Time of last update: 2024-10-05 18:52:39

Author of last update: Melvin.boenninger