cysP
168
sulfate transport in via proton symport
locus
BSU_15580
Molecular weight
36.68 kDa
pI
10.27
function
sulfate uptake
product
sulfate transport in via proton symport
essential
no
ec
null
synonyms
cysP, ylnA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0306 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,631,095 1,632,159
The protein
Protein family
inorganic phosphate transporter (PiT) (TC 2.A.20) family (with [protein|BBFA6A5EE16CE6203AF89573F87678395277C9E8|pit], according to UniProt)
Structure
[AF|O34734]
[wiki|Localization]
cell membrane
Expression and Regulation
Operons
genes
[gene|51EB09C122A7166D662AE72842A44EC5FBA03134|cysH]-[gene|58A5A7F12664EC38AC21E24C1AD89671D7E648CF|cysP]-[gene|6CF2A9A517B641C44C0B46EF242BC5E668EA846B|sat]-[gene|3C71659E4868744A9301C26608EABF7B98217DCF|cysC]-[gene|92831D5A8E07A18BA6C6978123769D00D685BB45|ylnD]-[gene|9349C4646A56F933041EBE750F1BE86BAE7A60D9|sirB]-[gene|8BAB9B12D9D58A45446DC6CB7F48869089800FD3|ylnF]
description
[Pubmed|11004190]
regulation
induced by methionine starvation ([wiki|S-box]) [Pubmed|10094622]
the [wiki|S-box] RNA is degraded by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] [pubmed|29794222]
regulatory mechanism
[protein|50930C56C27D22715620A350220E3C56ADB41020|cymR]: transcription repression, [pubmed|], in [regulon|protein:50930C56C27D22715620A350220E3C56ADB41020|cymR regulon]
S-box: RNA switch, , the [wiki|S-box] [wiki|riboswitch] binds S-adenosylmethionine resulting in termination [Pubmed|10094622], in [regulon|other_regulator:S-box|S-box]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|11004190], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
GP4479 (trpC2 Δ[gene|58A5A7F12664EC38AC21E24C1AD89671D7E648CF|cysP]::neo), available in [wiki|Jörg Stülke]'s lab
MGNA-B365 (ylnA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1364 NBRP B. subtilis, Japan]
BKE15580 ([gene|58A5A7F12664EC38AC21E24C1AD89671D7E648CF|cysP]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE15580 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GGCTAATTCCATTTTGCAGC, downstream forward: _UP4_TGATCATTAATCTGAGTAAT
BKK15580 ([gene|58A5A7F12664EC38AC21E24C1AD89671D7E648CF|cysP]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK15580 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GGCTAATTCCATTTTGCAGC, downstream forward: _UP4_TGATCATTAATCTGAGTAAT
labs
[[Isabelle Martin-Verstraete]], Institute Pasteur, Paris, France
References
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Time of last update: 2025-04-10 04:36:53
Author of last update: Robert.warneke