ybgG
168
homocysteine methyltransferase
locus
BSU_02410
Molecular weight
34.58 kDa
pI
4.86
function
biosynthesis of methionine
product
homocysteine methyltransferase
essential
no
synonyms
ybgG
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2040 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
261,656 262,603
The protein
Catalyzed reaction/ biological activity
S-methyl-L-methionine + L-homocysteine --> 2 L-methionine (according to UniProt)
[wiki|Domains]
Hcy-binding domain (aa 2-309) (according to UniProt)
[wiki|Cofactors]
Zn2+ (according to UniProt)
Structure
[PDB|5DML] (from ''Escherichia coli'', 52% identity) [pubmed|26564203]
[AF|O31463]
Expression and Regulation
Operons
genes
[gene|577723B2BF662A44D55DC84444ED64276D8DED17|ybgG]
description
[Pubmed|15995196]
genes
[gene|577723B2BF662A44D55DC84444ED64276D8DED17|ybgG]-[gene|B6A920650919D5BBBD75CCA58C30A0D8ECE64DA3|ybgF]
description
[pubmed|22383849]
Biological materials
Mutant
MGNA-B941 (ybgG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1940 NBRP B. subtilis, Japan]
BKE02410 ([gene|577723B2BF662A44D55DC84444ED64276D8DED17|ybgG]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE02410 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGAATGTACCGATGCCT, downstream forward: _UP4_TGACTTATCGGAATAGTTTG
BKK02410 ([gene|577723B2BF662A44D55DC84444ED64276D8DED17|ybgG]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK02410 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGAATGTACCGATGCCT, downstream forward: _UP4_TGACTTATCGGAATAGTTTG
References
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Time of last update: 2025-04-02 01:59:57
Author of last update: Melvin.boenninger