yvsH
168
putative lysine transporter
locus
BSU_33330
Molecular weight
50.09 kDa
pI
9.74
function
uptake of lysine
product
putative lysine transporter
essential
no
synonyms
yvsH, lysP
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0531 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,419,656 3,421,065
The protein
Protein family
[wiki|amino acid-polyamine-organocation (APC) superfamily] (according to UniProt)
Structure
[PDB|3LRB] (from ''E. coli'', 32% identity) [Pubmed|19478139]
[AF|O32204]
[wiki|Localization]
cell membrane [Pubmed|18763711]
Expression and Regulation
Operons
genes
[gene|5762418690734FB959506B7317208CCA1A340720|yvsH]
description
[pubmed|22383849]
regulation
antitermination is modulated by [protein|43CFA3477B4EEB4CE0B2DF63ED2B5EDB171E79C7|nusG]-dependent transcription pausing just upstream of the [protein|search|L-box] [pubmed|39494516]
regulatory mechanism
L-box: RNA switch, via a riboswitch, in [regulon|other_regulator:L-box|L-box]
Biological materials
Mutant
GP4153 (Δ[gene|5762418690734FB959506B7317208CCA1A340720|yvsH]::''aphA3''), available in [wiki|Jörg Stülke]'s lab
MGNA-B067 (yvsH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1066 NBRP B. subtilis, Japan]
BKE33330 ([gene|5762418690734FB959506B7317208CCA1A340720|yvsH]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33330 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCCAGTACCTCCATGAT, downstream forward: _UP4_TAATGAAAAGACACCTGATT
BKK33330 ([gene|5762418690734FB959506B7317208CCA1A340720|yvsH]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33330 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCCAGTACCTCCATGAT, downstream forward: _UP4_TAATGAAAAGACACCTGATT
References
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Time of last update: 2024-11-20 07:43:58
Author of last update: Jstuelk