yuaI
168
unknown
locus
BSU_31000
Molecular weight
19.70 kDa
pI
5.14
function
unknown
product
unknown
essential
no
synonyms
yuaI
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1247 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,179,926 3,180,447
The protein
Catalyzed reaction/ biological activity
[protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|sigW]-dependent expression of ''[gene|5D5D9A544295DD9B55C75A8CF47AB19935E740C6|fabF]'' and the ''[gene|FFBB9B236B7D532D45FE0593B793E28E051BE7A2|yuaF]-[gene|61893B4EB53FBBB9AD8BEEEFFCEFD0FC64544D6F|floT]-[gene|56345EA776E1C5664EF1F2D1AF5CE3E5F40AD442|yuaI]'' operon result in reduced membrane fluidity [Pubmed|21542858,22178969]
Protein family
[wiki|Acetyltransferase family] (according to UniProt)
[wiki|Domains]
[wiki|N-acetyltransferase domain] (aa 2-171) (according to UniProt)
Structure
[PDB|1WK4] (from Thermus thermophilus, 40% identity)
[AF|O32075]
Expression and Regulation
Operons
genes
[gene|FFBB9B236B7D532D45FE0593B793E28E051BE7A2|yuaF]-[gene|61893B4EB53FBBB9AD8BEEEFFCEFD0FC64544D6F|floT]-[gene|56345EA776E1C5664EF1F2D1AF5CE3E5F40AD442|yuaI]
description
[Pubmed|9987136]
regulation
expressed upon cell wall stress ([protein|search|SigW]) [Pubmed|9987136]
sigma factors
[protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|sigW]: sigma factor, [Pubmed|9987136], in [regulon|protein:3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|sigW regulon]
Biological materials
Mutant
MGNA-A221 (yuaI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/221 NBRP B. subtilis, Japan]
BKE31000 ([gene|56345EA776E1C5664EF1F2D1AF5CE3E5F40AD442|yuaI]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE31000 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TACCATACGGTTCTGCCCTT, downstream forward: _UP4_TAACGAAAAATCCCCCAGCG
BKK31000 ([gene|56345EA776E1C5664EF1F2D1AF5CE3E5F40AD442|yuaI]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK31000 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TACCATACGGTTCTGCCCTT, downstream forward: _UP4_TAACGAAAAATCCCCCAGCG
References
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Time of last update: 2024-12-05 12:05:06
Author of last update: Melvin.boenninger