ylaC
168
[wiki|RNA polymerase] ECF-type [wiki|sigma factor] YlaC
locus
BSU_14730
Molecular weight
20.78 kDa
pI
9.28
function
[category|SW.3.2.1|Transcription]
product
[wiki|RNA polymerase] ECF-type [wiki|sigma factor] YlaC
essential
no
synonyms
ylaC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1595 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,544,085 1,544,606
The protein
Protein family
[wiki|Sigma-70 factor family] (according to UniProt)
[wiki|ECF subfamily] (according to UniProt)
Structure
[PDB|5WUQ] ([protein|search|SigW ]in complex with the cytoplasmic domain of [protein|4E720917045032E8B45CB8AF6E5C13AE0E48EE33|rsiW], 33% identity) [pubmed|28319136]
[AF|O07627]
Effectors of protein activity
[protein|B454D14B33E2C11F0BB0A1D1BB743FA64981A966|ylaD] acts as anti-sigma [Pubmed|16728958]
Expression and Regulation
Operons
genes
[gene|6BB9336E8F5007274026A89BFC3744B52F28E42D|ylaA]-[gene|0703D458DB489F49150DD9E3477A87DC354A7B7F|ylaB]-[gene|544344B61A804F367BB726976E0C87B61998490A|ylaC]-[gene|B454D14B33E2C11F0BB0A1D1BB743FA64981A966|ylaD]
description
[Pubmed|16501307]
regulation
[protein|search|Spx]: transcription activation [Pubmed|16501307]
regulatory mechanism
[protein|2C6386E9A63F410558D168798D077DF91590F454|spx]: activation, [Pubmed|16501307], in [regulon|protein:2C6386E9A63F410558D168798D077DF91590F454|spx regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|16501307], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
[protein|544344B61A804F367BB726976E0C87B61998490A|ylaC]: sigma factor, [Pubmed|16501307], in [regulon|protein:544344B61A804F367BB726976E0C87B61998490A|ylaC regulon]
genes
[gene|544344B61A804F367BB726976E0C87B61998490A|ylaC]-[gene|B454D14B33E2C11F0BB0A1D1BB743FA64981A966|ylaD]
description
[Pubmed|16501307]
regulation
[protein|search|Spx]: transcription activation [Pubmed|16501307]
Biological materials
Mutant
MGNA-B356 (ylaC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1355 NBRP B. subtilis, Japan]
1A908 ( ''ylaC''::''kan''), [Pubmed|15838020], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A908&Search=1A908 BGSC]
BKE14730 ([gene|544344B61A804F367BB726976E0C87B61998490A|ylaC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE14730 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CTCAATGGAATCCCTATGCT, downstream forward: _UP4_AAAAGTAGAGAGGAGGAGCG
BKK14730 ([gene|544344B61A804F367BB726976E0C87B61998490A|ylaC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK14730 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CTCAATGGAATCCCTATGCT, downstream forward: _UP4_AAAAGTAGAGAGGAGGAGCG
References
Reviews
Original Publications
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Time of last update: 2024-12-30 11:05:52
Author of last update: Jstuelk