ytnP
168
lactonase-homolog protein, inhibits the signalling pathway required for the streptomycin production and development of aerial mycelium in Streptomyces griseus
locus
BSU_29890
Molecular weight
29.02 kDa
pI
5.93
function
defense against competing bacteria
product
lactonase-homolog protein
essential
no
synonyms
ytnP
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0491 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,058,631 3,059,401
The protein
Protein family
[wiki|metallo-beta-lactamase superfamily] (according to UniProt)
Structure
[PDB|3ESH] (from Staphylococcus aureus, 50% identity)
[AF|O34760]
Modification
phosphorylation on Ser-36 [Pubmed|17218307]
Expression and Regulation
Operons
genes
[gene|53259B300509E6B6DAF3ED106D1DDEDC99B5532B|ytnP]-[gene|BBBCD5F56779895189E21076AF165B901F654534|malS]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-A511 (ytnP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/511 NBRP B. subtilis, Japan]
BKE29890 ([gene|53259B300509E6B6DAF3ED106D1DDEDC99B5532B|ytnP]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE29890 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGGCGCCTCCGTCCATAT, downstream forward: _UP4_TAGCATATTTTTATGTTTAC
BKK29890 ([gene|53259B300509E6B6DAF3ED106D1DDEDC99B5532B|ytnP]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK29890 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGGCGCCTCCGTCCATAT, downstream forward: _UP4_TAGCATATTTTTATGTTTAC
References
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Time of last update: 2024-10-05 19:16:38
Author of last update: Jstuelk