yfiY

yfiY
168

[wiki|ABC transporter for the siderophore schizokinen and arthrobactin (binding protein), works with ATPase [protein|5C52DB31F378E49AABE5D937DD901A68F3810477|yusV]

locus
BSU_08440
Molecular weight
36.15 kDa
pI
7.17
Protein length
Gene length
function
[wiki|acquisition of iron]
product
[wiki|ABC transporter] for the siderophore schizokinen and arthrobactin (binding protein)
essential
no
synonyms
yfiY

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0614 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
919,366  920,343
Phenotypes of a mutant
poor growth with the xenosiderophores arthrobactin or aerobactin as single source of iron [Pubmed|23220087]
The protein
Protein family
[wiki|Bacterial solute-binding protein 8 family] (according to UniProt)
[wiki|Domains]
[wiki|Fe/B12 periplasmic-binding domain] (aa 56-325) (according to UniProt)
Structure
[PDB|3TNY] (from B. cereus, 57% identity)
[AF|O31567]
Modification
phosphorylation on (Ser-290 OR Thr-302) [Pubmed|17218307]
[wiki|Localization]
associated to the membrane (via [protein|34A7E22B4EF118EF5A76F8CC2DABBB023BC9A2E9|yfhA]-[protein|81494D4E7E52531802C3C0D0073739DA9375F5DF|yfiZ]) [Pubmed|10092453,18763711]
extracellular (signal peptide) [Pubmed|18957862]
Expression and Regulation
Operons
genes
[gene|521246EDA87A00F1B5E0792EC7AF1EF2B11C1C3C|yfiY]
description
[pubmed|22383849]
regulation
repressed unless the cells enter an iron starvation ([protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur]) [Pubmed|12354229]
regulatory mechanism
[protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur]: repression, [pubmed|12354229], in [regulon|protein:F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur regulon]
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[gene|521246EDA87A00F1B5E0792EC7AF1EF2B11C1C3C|yfiY]

2024-09-20 10:00:43

Jstuelk

62

67f81f7fe530899ce1275d9b6bd64adee7402713

059A1F7FF037788650F735F77FCFF3CDF34709A6

Biological materials
Mutant
MGNA-C311 (yfiY::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2309 NBRP B. subtilis, Japan]
BKE08440 ([gene|521246EDA87A00F1B5E0792EC7AF1EF2B11C1C3C|yfiY]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE08440 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCTTTTTCCTCCCAATAT,  downstream forward: _UP4_AAATAAAAAAAGACTCCGTC
BKK08440 ([gene|521246EDA87A00F1B5E0792EC7AF1EF2B11C1C3C|yfiY]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK08440 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCTTTTTCCTCCCAATAT,  downstream forward: _UP4_AAATAAAAAAAGACTCCGTC
References
36815589,10092453,16672620,12354229,18957862,18763711,17218307,23220087,23199363

521246EDA87A00F1B5E0792EC7AF1EF2B11C1C3C

Page visits: 5167

Time of last update: 2024-10-03 17:39:05

Author of last update: Jstuelk