rplS

rplS
168

ribosomal protein bL19

locus
BSU_16040
Molecular weight
13.61 kDa
pI
11.29
Protein length
Gene length
function
translation
product
ribosomal protein L19 (bL19)
essential
yes
synonyms
rplS

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0335 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,676,033  1,676,389
Phenotypes of a mutant
essential [Pubmed|23002217,12682299]
Visit Sartorius.com Visit Sartorius.com
Advertisement
The protein
Protein family
bacterial [wiki|ribosomal protein] bL19 family (single member, according to UniProt)
Structure
[PDB|3J9W] (the [wiki|ribosome]) [Pubmed|25903689]
[AF|O31742]
Additional information
this ribosomal protein is lacking in some organisms with very small genomes [pubmed|33753464]
Expression and Regulation
Operons
genes
[gene|8F559BFC80FE56EA0389A2336F4E9E6908562BCB|ylxM]-[gene|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|ffh]-[gene|25C4850812DC216C1BEFBF07DCA71CC6820930B0|rpsP]-[gene|67FB5F6FB0B2701BD8E4FDD8DF06B236DE6A2599|khpA]-[gene|0AB1FB44E8F28944B82B5EF14A9CDCFEE46DB76B|ylqD]-[gene|34B0FA6E7E25D1E5D8A54B70F5562BD0BD05B498|rimM]-[gene|885ECD9FAAC8BC95D32F049825D6B6244C046112|trmD]-[gene|51368512B8322EDBCA92674EC2B97CF26087D8A9|rplS]
description
[Pubmed|29794222]
regulation
the mRNA is processed between [gene|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|ffh] and [gene|25C4850812DC216C1BEFBF07DCA71CC6820930B0|rpsP] by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y], this requires the [protein|EE52DFA35B935E551871D079A9BE877DB2001A3B|ricA]-[protein|6C9A092F38739A3759793EF8B496569CD02C2E3F|ricF]-[protein|EBD15C174A03B7FCDFFE4C5DB5D86E93F1B9CAC4|ricT] complex [Pubmed|29794222]
expression
expression is decreased upon depletion of tRNA maturation factors [gene|57A79AAF00243B5E058FA901D43AA7B55CA33F63|rnpB] or [gene|C40C5D35ED53D343C8200248FCCB010BAB388054|rnz] [pubmed|36840557]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|8335643], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Open in new tab

[gene|8F559BFC80FE56EA0389A2336F4E9E6908562BCB|ylxM]→[gene|51368512B8322EDBCA92674EC2B97CF26087D8A9|rplS]

2024-07-02 16:02:41

Jstuelk

101

4F2FF9A3B937EE85312D0B0F9DA494E4B44E2297

417C7007C2492335257F8AEF606BB8627753757F

genes
[gene|51368512B8322EDBCA92674EC2B97CF26087D8A9|rplS]
description
[pubmed|22383849]
regulation
likely autorepression of ''rplS'' expression upon binding of excess [protein|51368512B8322EDBCA92674EC2B97CF26087D8A9|rplS] to the untranslated region of the ''rplS'' mRNA [Pubmed|17616982]
[protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|rel] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
regulatory mechanism
stringent response: negative regulation, in [regulon|other_regulator:stringent response|stringent response]
Open in new tab

[gene|51368512B8322EDBCA92674EC2B97CF26087D8A9|rplS]

2024-07-03 16:49:37

Jstuelk

66

35d7616afe203aff1a0764fa5b4839350973035a

5F8199913EEE498622E64ED2A13E066C8B6EF3AA

genes
[gene|25C4850812DC216C1BEFBF07DCA71CC6820930B0|rpsP]-[gene|67FB5F6FB0B2701BD8E4FDD8DF06B236DE6A2599|khpA]-[gene|0AB1FB44E8F28944B82B5EF14A9CDCFEE46DB76B|ylqD]-[gene|34B0FA6E7E25D1E5D8A54B70F5562BD0BD05B498|rimM]-[gene|885ECD9FAAC8BC95D32F049825D6B6244C046112|trmD]-[gene|51368512B8322EDBCA92674EC2B97CF26087D8A9|rplS]
description
[Pubmed|36840557]
Open in new tab

[gene|25C4850812DC216C1BEFBF07DCA71CC6820930B0|rpsP]→[gene|51368512B8322EDBCA92674EC2B97CF26087D8A9|rplS]

2024-07-02 15:58:27

Jstuelk

44

B00427AA69EF576CAC3B8B5C44347F99001CAF0D

B00427AA69EF576CAC3B8B5C44347F99001CAF0D

References
36815589,19653700,23002217,25903689,17616982,33753464,36840557

51368512B8322EDBCA92674EC2B97CF26087D8A9

Page visits: 4769

Time of last update: 2024-07-14 21:35:54

Author of last update: Jstuelk