yhdY
168
mechanosensitive channel, similar to MscS
locus
BSU_09640
Molecular weight
42.38 kDa
pI
5.76
function
resistance to osmotic downshock
product
mechanosensitive channel, similar to MscS
essential
no
synonyms
yhdY
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0668 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,038,909 1,040,024
The protein
Protein family
[wiki|MscS (TC 1.A.23) family] (according to UniProt)
Structure
[PDB|4AGE] (MscS from E. coli, corresponds to aa 129 ... 358 of YhdY, 27% identity) [pubmed|23012406]
[AF|O07594]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|50DC162B3A7798F8D10B8373968AD333F197360B|yhdY]
description
[Pubmed|21815947]
additional information
the mRNA is cleaved by [protein|BAB297D18F94FFA67B8D12A684AB4D1BCDFB4981|RNase III] [PubMed|26883633]
Biological materials
Mutant
MGNA-A701 (yhdY::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/701 NBRP B. subtilis, Japan]
1A958 ( ''yhdY''::''erm''), [Pubmed|18310427], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A958&Search=1A958 BGSC]
1A958 ( ''yhdY''::''erm''), [Pubmed|18310427], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A958&Search=1A958 BGSC]
BKE09640 ([gene|50DC162B3A7798F8D10B8373968AD333F197360B|yhdY]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE09640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGACTGTCTCCCCTCTAT, downstream forward: _UP4_TAAAAGAGAGACTTCGTCTG
BKK09640 ([gene|50DC162B3A7798F8D10B8373968AD333F197360B|yhdY]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK09640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGACTGTCTCCCCTCTAT, downstream forward: _UP4_TAAAAGAGAGACTTCGTCTG
References
Reviews
Original Publications
Labs working on this gene/protein
[wiki|Erhard Bremer], University of Marburg, Germany [http://www.uni-marburg.de/fb17/fachgebiete/mikrobio/molmibi homepage]
Page visits: 1971
Time of last update: 2024-10-03 22:56:42
Author of last update: Jstuelk