serB
168
phosphoserine phosphatase, catalyzes the last step in serine biosynthesis
locus
BSU_28940
Molecular weight
29.36 kDa
pI
4.67
function
biosynthesis of serine
product
phosphoserine phoshatase
essential
no
synonyms
serB, ysaA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1011 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,958,434 2,959,216
Phenotypes of a mutant
auxotrophic for serine [Pubmed|28189581]
The protein
Catalyzed reaction/ biological activity
phosphoserine - serine + phosphate [Pubmed|28189581]
Protein family
[wiki|HAD superfamily] (according to UniProt)
Structure
[PDB|2GFH] (from mouse, 32% identity)
[AF|P94512]
Paralogous protein(s)
[protein|2E1E22349750C3EE9B6575EED30A82ED0D5F07F0|yfnB]
Expression and Regulation
Operons
genes
[gene|50417B2FA0ED2258A13B1E708514F055297599EF|serB]
description
[pubmed|22383849,8969504]
Biological materials
Mutant
MGNA-A998 [gene|50417B2FA0ED2258A13B1E708514F055297599EF|serB]::erm, available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/998 NBRP B. subtilis, Japan]
BKE28940 ([gene|50417B2FA0ED2258A13B1E708514F055297599EF|serB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE28940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATCTTCTCCTCTGCTT, downstream forward: _UP4_TAAAAAAAGCATGATCTCTT
BKK28940 ([gene|50417B2FA0ED2258A13B1E708514F055297599EF|serB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK28940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATCTTCTCCTCTGCTT, downstream forward: _UP4_TAAAAAAAGCATGATCTCTT
References
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Time of last update: 2025-04-15 06:04:46
Author of last update: Melvin.boenninger