phrH
168
secreted regulator of the activity of phosphatase [protein|BA85E2C2E2A6B76FAFA31EBDBF466324C9B021C8|rapH]
locus
BSU_06839
Molecular weight
6.30 kDa
pI
9.518
function
control of [wiki|sporulation] initiation
product
secreted regulator of the activity of phosphatase [protein|BA85E2C2E2A6B76FAFA31EBDBF466324C9B021C8|rapH]
essential
no
synonyms
phrH
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Coordinates
752,079 752,252
The protein
Protein family
[wiki|phr family] (according to UniProt)
Structure
[AF|Q59HN7]
[wiki|Localization]
secreted as hexapeptide TDRNTT [Pubmed|21908671], uptake by the ([protein|05752B9C4EA7ACD579D65D028B7DF1861F3840CB|oppD]-[protein|38AD697B6C9967B8BD7496E31264A21F6D0A9DEE|oppF])-([protein|B0A3C7B253FB1DA1D4BC9D1D564905ECE8A65BC1|oppB]-[protein|DDBCE73B6AF39E5D669475479186C93F287DA9FC|oppC])-[protein|302DFA46D73E18C4663468ED6033C55056744475|oppA] [wiki|ABC transporter] [Pubmed|21908671]
Expression and Regulation
Operons
genes
[gene|4FA7D6E6316A6FC71C10C692D125833263894020|phrH]
description
[Pubmed|21908671]
regulation
''[protein|search|rapH]'': repressed by [protein|search|RghR] [Pubmed|16553878]
regulatory mechanism
[protein|972401B6AF56EC67FE6F1C3FEA9E2A9FC77C7672|rghR]: repression, [Pubmed|16553878], in [regulon|protein:972401B6AF56EC67FE6F1C3FEA9E2A9FC77C7672|rghR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|21908671], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
genes
[gene|BA85E2C2E2A6B76FAFA31EBDBF466324C9B021C8|rapH]-[gene|4FA7D6E6316A6FC71C10C692D125833263894020|phrH]
description
[Pubmed|21908671]
regulation
''[protein|search|rapH]'': repressed by [protein|search|RghR] [Pubmed|16553878]
regulatory mechanism
[protein|972401B6AF56EC67FE6F1C3FEA9E2A9FC77C7672|rghR]: repression, [Pubmed|16553878], in [regulon|protein:972401B6AF56EC67FE6F1C3FEA9E2A9FC77C7672|rghR regulon]
[protein|08CFA2C72931A75532D4289BC1D18A826DE9F9CA|comK]: activation, [Pubmed|11948146,11918817], in [regulon|protein:08CFA2C72931A75532D4289BC1D18A826DE9F9CA|comK regulon]
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [Pubmed|20817675], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|21908671], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
BKE06839 ([gene|4FA7D6E6316A6FC71C10C692D125833263894020|phrH]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE06839 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AGCCAGACACATCATCACTT, downstream forward: _UP4_TAGGGCTTTTTCTTGCTTTA
BKK06839 ([gene|4FA7D6E6316A6FC71C10C692D125833263894020|phrH]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK06839 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AGCCAGACACATCATCACTT, downstream forward: _UP4_TAGGGCTTTTTCTTGCTTTA
References
Reviews
Original Publications
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Time of last update: 2024-10-12 10:07:02
Author of last update: Jstuelk