spoVFB

spoVFB
168

dipicolinate synthase (subunit B)

locus
BSU_16740
Molecular weight
21.72 kDa
pI
6.15
Protein length
Gene length
function
dipicolic acid production
product
dipicolinate synthase (subunit B)
essential
no
synonyms
spoVFB, dpaB

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5843 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,745,263  1,745,865
The protein
Catalyzed reaction/ biological activity
(S)-2,3-dihydrodipicolinate + NADP+ --> dipicolinate + H+ + NADPH (according to UniProt)
Structure
[PDB|3MCU] (from B. cereus, 72% identity)
[AF|Q04810]
Expression and Regulation
Operons
genes
[gene|3DA80060554B78E9DC2189CECB78680095B08B32|spoVFA]-[gene|4D93A13DB9DC55A49525BFF4FD589F4FF67D50E8|spoVFB]-[gene|564A2F43F8AABE97FC8F0B1B3382A9F31F02FA18|asd]-[gene|6D6718AC72C9D86EDE16B191EDAB3ABA488B689B|dapG]-[gene|00B4CA4E25858A56F9D4E0ADEE2643F203FEC613|dapA]
description
[Pubmed|8098035]
regulation
expressed late during sporulation in the mother cell ([protein|search|SigK]) [Pubmed|15699190,8098035]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|15699190,8098035], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
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[gene|3DA80060554B78E9DC2189CECB78680095B08B32|spoVFA]→[gene|00B4CA4E25858A56F9D4E0ADEE2643F203FEC613|dapA]

2024-10-02 05:37:23

ghost

96

9f1758bf801d23548827e9d03f6ca9d0c2e6746d

C373CB045AB9232B86B60761B90C3510E98A06A8

Biological materials
Mutant
BKE16740 ([gene|4D93A13DB9DC55A49525BFF4FD589F4FF67D50E8|spoVFB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE16740 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TTTTCCTTTTAATGACGACA,  downstream forward: _UP4_TAAATTTACAGAAAATCTTT
BKK16740 ([gene|4D93A13DB9DC55A49525BFF4FD589F4FF67D50E8|spoVFB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK16740 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TTTTCCTTTTAATGACGACA,  downstream forward: _UP4_TAAATTTACAGAAAATCTTT
References
8345520,8098035,15699190,35638784

4D93A13DB9DC55A49525BFF4FD589F4FF67D50E8

Page visits: 2526

Time of last update: 2024-10-02 23:56:18

Author of last update: Jstuelk