rhgK
168
two-component sensor kinase
locus
BSU_06950
Molecular weight
66.17 kDa
pI
7.28
function
unknown
product
two-component sensor kinase
essential
no
ec
null
synonyms
yesM
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2972 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
758,719 760,452
The protein
Catalyzed reaction/ biological activity
autophosphorylation, phosphorylation of [protein|F09661C8A483D0FC796204102021104A4373F895|rhgL]
ATP + protein L-histidine --> ADP + protein N-phospho-L-histidine (according to UniProt)
[wiki|Domains]
two transmembrane segments
[wiki|HAMP domain] (aa 312-368) (according to UniProt)
[wiki|Histidine kinase domain] (aa 365-574) (according to UniProt)
Structure
[AF|O31516]
Modification
autophosphorylation on a His residue
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|EA17F9BBA4473C714711EB7577044402CD38B59C|yesL]-[gene|4A0961B9B760D4AA968B750ECE634B13039F9FC5|rhgK]-[gene|F09661C8A483D0FC796204102021104A4373F895|rhgL]
description
[pubmed|22383849]
regulation
induced by pectin [Pubmed|35881471]
repressed by glucose ([protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]) [pubmed|35881471]
regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
Biological materials
Mutant
MGNA-A945 (yesM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/945 NBRP B. subtilis, Japan]
BKE06950 ([gene|4A0961B9B760D4AA968B750ECE634B13039F9FC5|rhgK]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE06950 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GTACCAGCCAGCAACTCTTT, downstream forward: _UP4_CCGTGCCGAAATGAGGTGGT
BKK06950 ([gene|4A0961B9B760D4AA968B750ECE634B13039F9FC5|rhgK]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK06950 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GTACCAGCCAGCAACTCTTT, downstream forward: _UP4_CCGTGCCGAAATGAGGTGGT
References
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Time of last update: 2024-12-18 10:24:38
Author of last update: Jstuelk