mdtP
168
multidrug-efflux transporter
locus
BSU_32880
Molecular weight
57.78 kDa
pI
9.84
function
multidrug resistance
product
multidrug-efflux transporter
essential
no
synonyms
mdtP, yusP
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2814 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,374,956 3,376,581
The protein
Protein family
[wiki|major facilitator superfamily] (according to UniProt)
[wiki|EmrB family] (according to UniProt)
Structure
[AF|O32182]
[wiki|Localization]
cell membrane (according to UniProt), membrane associated [Pubmed|18763711]
Expression and Regulation
Operons
genes
[gene|795D70E8A4D750140D6B1AA4BFEBD25C2A389C85|mdtR]-[gene|45C61C1584A851676F15A2249F3F1092863C5AA5|mdtP]
description
[Pubmed|19286808]
regulatory mechanism
[protein|795D70E8A4D750140D6B1AA4BFEBD25C2A389C85|mdtR]: repression, [Pubmed|19286808], in [regulon|protein:795D70E8A4D750140D6B1AA4BFEBD25C2A389C85|mdtR regulon]
Biological materials
Mutant
MGNA-A601 (yusP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/601 NBRP B. subtilis, Japan]
BP70 (spc) available in [wiki|Fabian Commichau]'s lab
BKE32880 ([gene|45C61C1584A851676F15A2249F3F1092863C5AA5|mdtP]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE32880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTGTTTGCCTTCTTTACTCA, downstream forward: _UP4_TAATAGAGCACCCCGCGGGT
BKK32880 ([gene|45C61C1584A851676F15A2249F3F1092863C5AA5|mdtP]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK32880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTGTTTGCCTTCTTTACTCA, downstream forward: _UP4_TAATAGAGCACCCCGCGGGT
References
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Time of last update: 2024-12-19 19:20:19
Author of last update: Melvin.boenninger