yciB
168
putative L,D-transpeptidase
locus
BSU_03350
Molecular weight
21.94 kDa
pI
6.18
function
unknown
product
putative L,D-transpeptidase
essential
no
synonyms
yciB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1376 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
365,170 365,754
The protein
Protein family
YkuD family (with [protein|6F256986E591DB82974A7F54EB1CE0C024A6F63B|ldt] and [protein|293794B65B9EEB7F049138F73893303BABFB9A2A|yqjB], according to UniProt)
Structure
[PDB|4LZH] (from Klebsiella pneumoniae, 27% identity)
[AF|C0SP99]
[wiki|Localization]
lipoprotein, cell membrane at the cell poles [Pubmed|20013255]
Expression and Regulation
Operons
genes
[gene|93380E8EEB672C14C9BE2B5A6D8573FBCA149514|folEB]-[gene|456AF184261976FAA73359E81443F7035F457D07|yciB]-[gene|F735802BB483C2C5437240AB2E9FC340EAA5B353|yczL]-[gene|75DB07A2704FEC2932BD0CDD24E2B3454E9551E1|zagA]
description
[Pubmed|9811636]
regulation
[wiki|folE2]: induced by zinc starvation ([protein|A0CD8CCB54AE9F10DE3C876FB47B9877C303862D|zur]) [Pubmed|12426338]
regulatory mechanism
[protein|A0CD8CCB54AE9F10DE3C876FB47B9877C303862D|zur]: repression, in the presence of zinc [Pubmed|12426338], in [regulon|protein:A0CD8CCB54AE9F10DE3C876FB47B9877C303862D|zur regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|12426338], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
MGNA-B998 (yciB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1997 NBRP B. subtilis, Japan]
BKE03350 ([gene|456AF184261976FAA73359E81443F7035F457D07|yciB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03350 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGCAATAATGAATAATGAGA, downstream forward: _UP4_TGAATTGAAAACCGTTGACA
BKK03350 ([gene|456AF184261976FAA73359E81443F7035F457D07|yciB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03350 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGCAATAATGAATAATGAGA, downstream forward: _UP4_TGAATTGAAAACCGTTGACA
References
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Time of last update: 2024-12-21 22:28:01
Author of last update: Jstuelk