paiA
168
spermine/spermidine-N-acetyltransferase
locus
BSU_32150
Molecular weight
19.87 kDa
pI
5.02
function
control of intracellular polyamine concentrations
product
spermine/spermidine-N-acetyltransferase
essential
no
synonyms
paiA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0456 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,304,743 3,305,261
The protein
Catalyzed reaction/ biological activity
acetyl-CoA + alkane-α,ω-diamine --> N-acetylalkane-α,ω-diamine + CoA + H+ (according to UniProt)
[wiki|Domains]
[wiki|N-acetyltransferase domain] (aa 3-172) (according to UniProt)
Structure
[PDB|1TIQ]
[AF|P21340]
Expression and Regulation
Operons
genes
[gene|430E15D61FCCA20FAC2BCCF504A12070794372FD|paiA]-[gene|511CFC625D79AAA8B78809651684E4E409337AFA|paiB]
description
[Pubmed|27965289]
Biological materials
Mutant
BKE32150 ([gene|430E15D61FCCA20FAC2BCCF504A12070794372FD|paiA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE32150 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGTTCGGATTCAGCCCC, downstream forward: _UP4_TAATATTTTTCGAAGGGTGG
BKK32150 ([gene|430E15D61FCCA20FAC2BCCF504A12070794372FD|paiA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK32150 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGTTCGGATTCAGCCCC, downstream forward: _UP4_TAATATTTTTCGAAGGGTGG
References
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Time of last update: 2025-04-03 13:54:46
Author of last update: Melvin.boenninger