tlpC
168
membrane-bound chemotaxis receptor, methyl-accepting chemotaxis protein
locus
BSU_03440
Molecular weight
61.62 kDa
pI
4.93
function
control of chemotaxis
product
methyl-accepting chemotaxis protein
essential
no
synonyms
tlpC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG3290 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
372,771 374,492
The protein
[wiki|Domains]
[wiki|HAMP domain] (aa 194-246) (according to UniProt)
[wiki|Methyl-accepting transducer domain] (aa 280-544) (according to UniProt)
Structure
[PDB|6S1K] (from E. coli, corresponds to aa 151 ... 498, 28.6% identity) [pubmed|31925330]
[AF|P39209]
[wiki|Localization]
cell membrane [Pubmed|21515776]
Expression and Regulation
Operons
genes
[gene|426253699CA4183F2E1023169C3B80AFA15108E4|tlpC]
description
[Pubmed|7921238,7746143]
sigma factors
[protein|7024E4162A6D827069F882FDEACA696EBC05DD40|sigD]: sigma factor, [Pubmed|7921238], in [regulon|protein:7024E4162A6D827069F882FDEACA696EBC05DD40|sigD regulon]
additional information
in minimal medium,TlpC is present with 5,400 /- 1700 molecules per cell [PubMed|21515776]
Biological materials
Mutant
BKE03440 ([gene|426253699CA4183F2E1023169C3B80AFA15108E4|tlpC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03440 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAATTCCTCCCTTTACGA, downstream forward: _UP4_TGATGACTTACTATCATTAT
BKK03440 ([gene|426253699CA4183F2E1023169C3B80AFA15108E4|tlpC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03440 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAATTCCTCCCTTTACGA, downstream forward: _UP4_TGATGACTTACTATCATTAT
References
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Time of last update: 2024-12-19 22:56:47
Author of last update: Jstuelk