tlpC

tlpC
168

membrane-bound chemotaxis receptor, methyl-accepting chemotaxis protein

locus
BSU_03440
Molecular weight
61.62 kDa
pI
4.93
Protein length
Gene length
function
control of chemotaxis
product
methyl-accepting chemotaxis protein
essential
no
synonyms
tlpC

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3290 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
372,771  374,492
The protein
[wiki|Domains]
[wiki|HAMP domain] (aa 194-246) (according to UniProt)
[wiki|Methyl-accepting transducer domain] (aa 280-544) (according to UniProt)
Structure
[PDB|6S1K] (from E. coli, corresponds to aa 151 ... 498, 28.6% identity) [pubmed|31925330]
[AF|P39209]
[wiki|Localization]
cell membrane [Pubmed|21515776]
Expression and Regulation
Operons
genes
[gene|426253699CA4183F2E1023169C3B80AFA15108E4|tlpC]
description
[Pubmed|7921238,7746143]
sigma factors
[protein|7024E4162A6D827069F882FDEACA696EBC05DD40|sigD]: sigma factor, [Pubmed|7921238], in [regulon|protein:7024E4162A6D827069F882FDEACA696EBC05DD40|sigD regulon]
additional information
in minimal medium,TlpC is present with 5,400 /- 1700 molecules per cell [PubMed|21515776]
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[gene|426253699CA4183F2E1023169C3B80AFA15108E4|tlpC]

2024-09-08 11:29:39

ghost

50

4f68cde92296f3427e867b0170571402abb7020c

4B00462C7D1557731FB8554E4922113BFF68DFFA

Biological materials
Mutant
BKE03440 ([gene|426253699CA4183F2E1023169C3B80AFA15108E4|tlpC]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03440 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATAATTCCTCCCTTTACGA,  downstream forward: _UP4_TGATGACTTACTATCATTAT
BKK03440 ([gene|426253699CA4183F2E1023169C3B80AFA15108E4|tlpC]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03440 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATAATTCCTCCCTTTACGA,  downstream forward: _UP4_TGATGACTTACTATCATTAT
References
7921238,7746143,21515776,27899502,31925330

426253699CA4183F2E1023169C3B80AFA15108E4

Page visits: 3752

Time of last update: 2024-10-08 23:32:34

Author of last update: Jstuelk